School of Psychiatry, University of New South Wales, Sydney, Australia.
Int Psychogeriatr. 2010 May;22(3):426-36. doi: 10.1017/S1041610209991335. Epub 2009 Dec 15.
The aim of this study was to determine levels, rates and progression of apathy in healthy older persons and to investigate factors associated with its progression.
Seventy-six healthy elderly subjects, aged 58-85 years (mean 69.9), who were recruited by general advertisement and through local community groups, participated as a control group for a longitudinal study of stroke patients. Data were collected on demographic, psychological, neuropsychological and neuroimaging (MRI) variables and apathy was rated by informants on the Apathy Evaluation Scale (AES).
Apathy scores and rates increased over 5 years, especially in men. Change of apathy was associated with informant ratings of cognitive decline in the years prior to baseline assessment but not to subsequent neuropsychological, neuroimaging or functional changes.
Apathy increases with age in otherwise healthy community-dwelling individuals, particularly in men.
本研究旨在确定健康老年人中淡漠的水平、发生率和进展，并探讨与其进展相关的因素。
76 名健康老年人（年龄 58-85 岁，平均 69.9 岁）通过一般广告和当地社区团体招募，作为中风患者纵向研究的对照组。收集人口统计学、心理学、神经心理学和神经影像学（MRI）变量的数据，并由知情人根据淡漠评估量表（AES）对淡漠进行评分。
淡漠评分和发生率在 5 年内增加，尤其是男性。淡漠的变化与基线评估前几年知情人对认知能力下降的评估有关，但与随后的神经心理学、神经影像学或功能变化无关。
在其他方面健康的社区居住者中，淡漠随着年龄的增长而增加，尤其是男性。
