拓展核糖体的世界。
Expanding the ribosomal universe.
机构信息
Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.
Department of Molecular Genetics, Microbiology, & Immunology, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ, USA.
出版信息
Structure. 2009 Dec 9;17(12):1547-1548. doi: 10.1016/j.str.2009.11.003.
Abstract
In this issue of Structure, Taylor et al. (2009) present the most complete model of an eukaryotic ribosome to date. This achievement represents a critical milestone along the path to structurally defining the unique aspects of the eukaryotic protein synthetic machinery.
摘要
在本期《结构》中，Taylor 等人（2009 年）呈现了迄今为止最完整的真核核糖体模型。这一成果代表了在结构上定义真核蛋白质合成机制独特方面的道路上的一个关键里程碑。
相似文献
1
Expanding the ribosomal universe.拓展核糖体的世界。
Structure. 2009 Dec 9;17(12):1547-1548. doi: 10.1016/j.str.2009.11.003.
2
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.Cryo-EM 结构和 rRNA 模型：5.5-A 分辨率下的翻译真核 80S 核糖体。
Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19748-53. doi: 10.1073/pnas.1009999107. Epub 2010 Oct 27.
3
Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.通过比较利什曼原虫和人类核糖体揭示了动基体特异性分裂 rRNA 的结构和稳定性。
Nat Commun. 2016 Oct 18;7:13223. doi: 10.1038/ncomms13223.
4
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome.真核生物核糖体蛋白在 5.5Å 冷冻电镜真核 80S 核糖体图谱中的定位。
Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19754-9. doi: 10.1073/pnas.1010005107. Epub 2010 Oct 25.
5
Eukaryotic Ribosome Assembly.真核生物核糖体组装。
Annu Rev Biochem. 2024 Aug;93(1):189-210. doi: 10.1146/annurev-biochem-030222-113611. Epub 2024 Jul 2.
6
Comprehensive molecular structure of the eukaryotic ribosome.真核生物核糖体的综合分子结构。
Structure. 2009 Dec 9;17(12):1591-1604. doi: 10.1016/j.str.2009.09.015.
7
A Puzzle of Life: Crafting Ribosomal Subunits.生命之谜：核糖体亚基的构成
Trends Biochem Sci. 2017 Aug;42(8):640-654. doi: 10.1016/j.tibs.2017.05.005. Epub 2017 Jun 1.
8
Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells.结构异质性核糖体在细菌细胞的蛋白质合成过程中协同发挥作用。
Nat Commun. 2025 Mar 20;16(1):2751. doi: 10.1038/s41467-025-57955-8.
9
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome.布鲁氏锥虫核糖体的高分辨率冷冻电子显微镜结构。
Nature. 2013 Feb 21;494(7437):385-9. doi: 10.1038/nature11872. Epub 2013 Feb 10.
10
Structure of the human 80S ribosome.人 80S 核糖体的结构。
Nature. 2015 Apr 30;520(7549):640-5. doi: 10.1038/nature14427. Epub 2015 Apr 22.
本文引用的文献
1
Single-particle reconstruction of biological macromolecules in electron microscopy--30 years.电子显微镜中单颗粒生物大分子重构——30 年。
Q Rev Biophys. 2009 Aug;42(3):139-58. doi: 10.1017/S0033583509990059.
2
Comprehensive molecular structure of the eukaryotic ribosome.真核生物核糖体的综合分子结构。
Structure. 2009 Dec 9;17(12):1591-1604. doi: 10.1016/j.str.2009.09.015.
3
The eukaryotic ribosome: current status and challenges.真核生物核糖体：现状与挑战
J Biol Chem. 2009 May 1;284(18):11761-5. doi: 10.1074/jbc.R800074200. Epub 2008 Dec 31.
4
Molecular basis of Diamond-Blackfan anemia: structure and function analysis of RPS19.先天性纯红细胞再生障碍性贫血的分子基础：RPS19的结构与功能分析
Nucleic Acids Res. 2007;35(17):5913-21. doi: 10.1093/nar/gkm626. Epub 2007 Aug 28.
5
Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation.修饰后的真核延伸因子2（eEF2）80S核糖体复合物结构揭示了GTP水解在转位过程中的作用。
EMBO J. 2007 May 2;26(9):2421-31. doi: 10.1038/sj.emboj.7601677. Epub 2007 Apr 19.
6
Amino acid incorporation in vitro by ribonucleoprotein particles detached from guinea pig liver microsomes.从豚鼠肝脏微粒体分离出的核糖核蛋白颗粒在体外的氨基酸掺入。
J Biol Chem. 1960 May;235:1419-24.
7
Atomic structures of the 30S subunit and its complexes with ligands and antibiotics.30S亚基及其与配体和抗生素复合物的原子结构。
Cold Spring Harb Symp Quant Biol. 2001;66:17-32. doi: 10.1101/sqb.2001.66.17.
8
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.2.4埃分辨率下大核糖体亚基的完整原子结构。
Science. 2000 Aug 11;289(5481):905-20. doi: 10.1126/science.289.5481.905.
9
Crystallization of Escherichia coli ribosomes.大肠杆菌核糖体的结晶
FEBS Lett. 1982 Sep 6;146(1):217-20. doi: 10.1016/0014-5793(82)80739-4.
Zotero 插件