Department of General and Social Psychiatry, Psychiatric University Hospital Zurich, Lenggstrasse 31, 8032 Zurich, Switzerland.
Psychiatry Res. 2010 Jan 30;175(1-2):58-62. doi: 10.1016/j.psychres.2008.11.003. Epub 2009 Dec 11.
In many countries fewer than 20% of individuals with schizophrenia receive depot antipsychotic medication. Frequently stated reasons are psychiatrist's, patient's and relative's objections to depot treatment. This is the first study that directly compares the attitudes to depot antipsychotics of psychiatrists, patients and relatives. A semi-structured questionnaire about their attitudes towards depot antipsychotics was completed by 255 participants (83 patients diagnosed with schizophrenic disorder, 81 psychiatrists in private practice and 91 relatives, not directly related to the patients). Patients were more negative towards depot injections than psychiatrists and relatives. They particularly fear to be constricted in their autonomy when treated with depot antipsychotics and that injections might be painful. About 67% of all patients in our sample did not receive information about depot antipsychotics from their psychiatrist. Less than 10% of psychiatrists offer depot treatment after a first psychotic episode. Psychiatrists use depot antipsychotics in a conservative way, although they attribute positive traits to the method. Patients' negative attitudes might relate to the low level of information. To enhance the use of depot antipsychotics, information practices of psychiatrists should be improved. Patients should be informed about different forms of treatment during early stages of the illness.
在许多国家，只有不到 20%的精神分裂症患者接受长效抗精神病药物治疗。经常提到的原因是精神科医生、患者和家属反对长效治疗。这是第一项直接比较精神科医生、患者和家属对长效抗精神病药物的态度的研究。255 名参与者（83 名被诊断为精神分裂症的患者、81 名私人执业的精神科医生和 91 名亲属，与患者没有直接关系）完成了一份关于他们对长效抗精神病药物态度的半结构式问卷。与精神科医生和家属相比，患者对长效注射的态度更为消极。他们特别担心在接受长效抗精神病药物治疗时会限制自己的自主权，并且担心注射会很痛苦。在我们的样本中，约 67%的患者没有从精神科医生那里获得长效抗精神病药物的信息。不到 10%的精神科医生在首次出现精神病发作后会提供长效治疗。精神科医生以保守的方式使用长效抗精神病药物，尽管他们认为这种方法有积极的特点。患者的消极态度可能与信息水平低有关。为了增加长效抗精神病药物的使用，应改善精神科医生的信息实践。应在疾病早期向患者告知不同的治疗形式。
