Neurorehabilitation Unit, Rehabilitation Department, Fondazione Istituto San Raffaele - G. Giglio, Cefalù (PA), Italy.
Clin Neurophysiol. 2010 Mar;121(3):274-80. doi: 10.1016/j.clinph.2009.11.008. Epub 2009 Dec 11.
To investigate the prognostic value of standard electroencephalogram (EEG) in predicting the improvement of the level of consciousness in patients suffering from severe disturbances of consciousness following coma caused by acute brain injuries.
A standard EEG was recorded at admission in our rehabilitation department in a total of 46 patients with impaired consciousness states following coma (22 patients with traumatic brain injuries, 24 patients with non-traumatic brain injuries). We quantified the EEG abnormalities using the scale of Synek (1988) and correlated them with the basal level of cognitive functioning (LCF) scale score and with its variation after three months.
EEG scores correlated with LCF scores at admission (p<0.01) and with LCF scores' variation after three months (p<0.01) in patients with traumatic brain injury; EEG scores correlated only with LCF scores variation after three months (p<0.01) in patients with non-traumatic brain injury.
Standard EEG, analysed using the Synek scale, has a good prognostic value in both groups of patients with disorders of consciousness.
This work may have implications for clinical care, rehabilitative programs and medical-legal decisions in patients with impaired consciousness states following coma due to acute brain injuries.
研究标准脑电图（EEG）在预测急性脑损伤导致昏迷后意识障碍患者意识水平改善方面的预后价值。
在我们康复科共对 46 例昏迷后意识障碍的患者（22 例创伤性脑损伤，24 例非创伤性脑损伤）进行了标准 EEG 记录。我们使用 Synek（1988）量表量化了 EEG 异常，并将其与基础认知功能（LCF）量表评分及其三个月后的变化相关联。
EEG 评分与创伤性脑损伤患者入院时的 LCF 评分（p<0.01）和三个月后的 LCF 评分变化（p<0.01）相关；EEG 评分仅与非创伤性脑损伤患者三个月后的 LCF 评分变化相关（p<0.01）。
使用 Synek 量表分析的标准 EEG 在两组意识障碍患者中均具有良好的预后价值。
这项工作可能对急性脑损伤导致昏迷后意识障碍患者的临床护理、康复计划和医疗法律决策产生影响。
