Stücklschweiger G, Schad K A, Handl-Zeller L, Leitner H, Poier E, Hackl A
Universitätsklinik für Radiologie, Abteilung für Strahlentherapie, Graz.
Strahlenther Onkol. 1991 Feb;167(2):98-104.
For selective heating of superficially located or easily accessible tumors interstitial hyperthermia has become an increasing popular method in combination with interstitial radioactive implants. At our institution the hyperthermia treatment is performed utilizing the warm water system KHS-9, which is adapted to our Ir-192 high-dose-rate afterloading device, so that the same hollow needles for the interstitial radiation can be used for the heating procedure. So far, this technique has been applied for the treatment of primary and carcinomas, gynecological recurrences, and metastases of malignant melanomas after preceding in vitro measurements of temperature distribution. As a result both, in vitro and in vivo investigations showed good homogeneity of the temperature throughout the heated volume. Analysing the temperature data of in vivo measurements the maximum deviation of temperature was found to be 1.5 degrees C. When using a needle spacing of 8 mm, the temperature required for clinical application (42.5 degrees C) could be maintained in all heat treatments with a preselected water temperature of 46 degrees C to 49.5 degrees C.
对于浅表或易于接近的肿瘤的选择性加热，间质热疗已成为一种越来越受欢迎的与间质放射性植入物联合使用的方法。在我们机构，热疗治疗使用KHS - 9温水系统进行，该系统适用于我们的铱 - 192高剂量率后装装置，这样用于间质放射治疗的相同空心针可用于加热过程。到目前为止，在进行了温度分布的体外测量之后，该技术已应用于原发性和癌、妇科复发以及恶性黑色素瘤转移的治疗。结果，体外和体内研究均显示在整个加热体积内温度具有良好的均匀性。分析体内测量的温度数据发现，温度的最大偏差为1.5摄氏度。当使用8毫米的针间距时，在所有热疗中，将预选水温设置为46摄氏度至49.5摄氏度，可维持临床应用所需的温度（42.5摄氏度）。
