Levendag P C, Ruifrok A C, Marijnissen J P, van Putten W L, Visser A G
Dr. Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Strahlenther Onkol. 1989 Jan;165(1):56-60.
This paper deals with interstitial radiation therapy (RT), interstitial hyperthermia (HT) and interstitial photodynamic therapy (PDT). Its main focus, however, is to describe a single animal model in which the interaction of these three modalities, when applied by interstitial techniques, can be studied. To serve this purpose a special template was designed by which the parallel interaction of catheters (sources) with a fixed spacing was facilitated. If necessary, radiation sources could be fixed into the tumor during the computed treatment time. The applicability of this simple design is demonstrated by the preliminary findings of two conducted pilot studies, that is with the combination of interstitial PDT + HT and the combination of interstitial HT + RT.
本文论述了间质放射治疗（RT）、间质热疗（HT）和间质光动力疗法（PDT）。然而，其主要重点是描述一种单一动物模型，在该模型中可以研究这三种治疗方式通过间质技术应用时的相互作用。为实现这一目的，设计了一种特殊模板，以促进导管（源）以固定间距平行排列。如有必要，可在计算的治疗时间内将放射源固定在肿瘤中。两项初步先导研究的初步结果证明了这种简单设计的适用性，即间质PDT+HT联合应用以及间质HT+RT联合应用。
