Division of Chemistry and Materials, Manchester Metropolitan University, Manchester, UK.
Dent Mater. 2010 Mar;26(3):249-56. doi: 10.1016/j.dental.2009.11.002. Epub 2009 Dec 16.
Nickel chromium is widely used as a restorative material in dentistry but its biocompatibility is of concern as there are reports of patients suffering adverse effects caused by exposure to nickel-based restorations. The aim of this work was to quantify the amount of nickel released into solution from commercially available nickel-based alloys with varying compositions and to identify the potential use of thin films in further understanding the role of chromium in reducing nickel release.
Six commercially available nickel-based alloys were cast using the lost wax technique. Nickel chromium thin films were deposited onto silicon substrates by ion beam assisted physical vapor deposition. Both types of alloys were immersed into solution representative of saliva at pH 5 for 7 days. The amount of nickel released into solution was quantified by graphite-furnace atomic absorption spectrophotometry.
The amount of nickel released from commercially available cast alloys did not correspond to the amount of nickel within the alloy. The total amount of chromium and molybdenum within the alloys proved to be of greater influence. Increasing the amount of chromium in the thin film alloys reduced the amount of nickel released but this was not linear.
Differences in the composition of commercial cast alloys highlighted the importance of other elements within the alloy on reducing the amount of nickel released. The use of thin film alloys can be useful in further understanding how the composition of an alloy can affect the amount of nickel released.
镍铬被广泛用作牙科修复材料，但由于有报道称患者因接触含镍修复体而出现不良反应，其生物相容性令人担忧。本研究的目的是定量测定具有不同成分的市售镍基合金释放到溶液中的镍含量，并确定薄膜在进一步了解铬在减少镍释放中的作用方面的潜在用途。
采用失蜡技术铸造六种市售镍基合金。通过离子束辅助物理气相沉积在硅衬底上沉积镍铬薄膜。将这两种类型的合金在 pH 值为 5 的唾液溶液中浸泡 7 天。通过石墨炉原子吸收分光光度法定量测定释放到溶液中的镍量。
市售铸造合金释放的镍量与合金中的镍量不对应。合金中铬和钼的总量对镍释放量的影响更大。增加薄膜合金中铬的含量可以减少镍的释放量，但并非线性关系。
商业铸造合金成分的差异强调了合金中其他元素在减少镍释放量方面的重要性。薄膜合金的使用有助于进一步了解合金成分如何影响镍的释放量。
