不锈钢牙冠镍释放量的评估。
Assessment of nickel release from stainless steel crowns.
作者信息
Ramazani Nahid, Ahmadi Rahil, Darijani Mansure
机构信息
Assistant Professor, Children and Adolescent Health Research Center, Department of Pediatric Dentistry, Faculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Assistant Professor, Department of Pediatric Dentistry, Faculty of Dentistry, Shahed University, Tehran, Iran.
出版信息
J Dent (Tehran). 2014 May;11(3):328-34. Epub 2014 May 31.
OBJECTIVE
Adverse effects of dental materials, especially metals, have been an important issue in recent decades.
PURPOSE OF STUDY
The purpose of this study was to determine the amount of nickel released from stainless steel crowns in artificial saliva.
MATERIALS AND METHODS
In this in-vitro study, 270 stainless steel crowns were divided into five groups, each with nine subgroups. Each group (I to V) was comprised of four, five, six, seven and eight crowns, respectively. Each subgroup was placed in a polyethylene jar containing artificial saliva and held in an incubator at 37°C for four weeks. The amount of released nickel was determined on days 1, 7, 14, 21 and 28, using an atomic absorption spectrophotometer. Wilcoxon Signed-Rank and Kruskal-Wallis with Dunn's post hoc tests (SPSS software, v. 18) were used for statistical analysis at a significance level of 0.05.
RESULTS
The mean level of nickel on day 1 was more than that of day 7; this difference was statistically significant for all groups (P < 0.05), except for group II (P = 0.086). Also, the mean difference of released nickel between the groups was significant on day 1 (P = 0.006) and was insignificant on day 7 (P = 0.620). The nickel levels were zero on days 14, 21, and 28.
CONCLUSION
The amount of nickel was below the toxic level and did not exceed the dietary intake.
目的
近几十年来，牙科材料尤其是金属的不良反应一直是一个重要问题。
研究目的
本研究的目的是测定不锈钢牙冠在人工唾液中释放的镍含量。
材料与方法
在这项体外研究中，270个不锈钢牙冠被分为五组，每组有九个亚组。每组（I至V）分别由四个、五个、六个、七个和八个牙冠组成。每个亚组被放置在一个装有人工唾液的聚乙烯罐中，并在37°C的培养箱中放置四周。在第1、7、14、21和28天，使用原子吸收分光光度计测定释放的镍含量。采用Wilcoxon符号秩检验和Kruskal-Wallis检验以及Dunn事后检验（SPSS软件，v. 18）进行统计分析，显著性水平为0.05。
结果
第1天镍的平均水平高于第7天；除第二组外（P = 0.086），所有组的这种差异均具有统计学意义（P < 0.05）。此外，各组之间释放镍的平均差异在第1天具有显著性（P = 0.006），而在第7天不具有显著性（P = 0.620）。在第14、21和28天镍含量为零。
结论
镍含量低于毒性水平，未超过膳食摄入量。
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