National Cancer Control Institute, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 411-760, Republic of Korea.
Vaccine. 2010 Feb 17;28(7):1854-60. doi: 10.1016/j.vaccine.2009.11.079. Epub 2009 Dec 14.
We assessed adult male and female awareness and acceptance of human papillomavirus (HPV) infection and vaccination for cervical cancer prevention, as well as factors associated with willingness to be administered the HPV vaccine. A nationwide population-based interview survey was conducted in Korea. One thousand male and female adults were included with random sampling. Despite the fact that awareness of HPV infection (13.3%) and the preventive effect of HPV vaccination (8.6%) were low, willingness to vaccinate against HPV (55.0%) was relatively high, especially with regard to participants' daughters (77.0%). Those who were informed about HPV infection (adjusted odds ratio, aOR=2.5 and 95% confidence interval, CI=1.1-5.3 in males; aOR=2.5 and 95% CI=1.5-4.2 in females) or vaccination (aOR=2.9 and 95% CI=1.1-7.6 in males; aOR=2.9 and 95% CI=1.6-5.4 in females), or who perceived a susceptibility to HPV infection (aOR=3.6 and 95% CI=1.9-6.8 in males; aOR=2.8 and 95% CI=1.6-5.0 in females) were more accepting of vaccination than those who did not. Appropriate knowledge transfer, guidance from a health professional, and reductions in the cost of the vaccine are key issues in promoting awareness of HPV infection and vaccination for cervical cancer prevention.
我们评估了成年男性和女性对人乳头瘤病毒(HPV)感染和接种 HPV 疫苗预防宫颈癌的认知和接受程度,以及与接种 HPV 疫苗意愿相关的因素。在韩国进行了一项全国性的基于人群的访谈调查。采用随机抽样的方法纳入了 1000 名成年男性和女性。尽管 HPV 感染的认知率(13.3%)和 HPV 疫苗的预防效果(8.6%)较低,但接种 HPV 疫苗的意愿(55.0%)相对较高,尤其是对于参与者的女儿(77.0%)。那些了解 HPV 感染(男性调整后的优势比,aOR=2.5,95%置信区间,CI=1.1-5.3;女性 aOR=2.5,95%CI=1.5-4.2)或接种疫苗(男性 aOR=2.9,95%CI=1.1-7.6;女性 aOR=2.9,95%CI=1.6-5.4),或认为自己易感染 HPV(男性 aOR=3.6,95%CI=1.9-6.8;女性 aOR=2.8,95%CI=1.6-5.0)的人比没有这些认知的人更愿意接种疫苗。适当的知识传播、卫生专业人员的指导以及降低疫苗成本是提高 HPV 感染和接种 HPV 疫苗预防宫颈癌认知的关键问题。