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家庭每日经腹电刺激增加慢传输型便秘儿童的排便:一项初步研究。

Daily transabdominal electrical stimulation at home increased defecation in children with slow-transit constipation: a pilot study.

机构信息

School of Medicine, University of Melbourne, Melbourne 3050, Australia.

出版信息

J Pediatr Surg. 2009 Dec;44(12):2388-92. doi: 10.1016/j.jpedsurg.2009.07.063.

Abstract

PURPOSE

Transcutaneous electrical stimulation (TES) (3 sessions/wk) over the abdomen stimulated bowel functions in a randomized controlled trial. This pilot study assessed whether daily TES at home with a safe, portable machine would be possible and more efficacious than trial results.

METHODS

Eleven patients (6 male/5 female; mean age, 14 years; range, 12-18 years) with slow-transit constipation who relapsed or responded poorly in the trial were recruited (11 +/- 5 months later). An EPM-IF-4160 (Fuji Dynamics, Hong Kong) portable machine (sine waveform, 4 kHz carrier frequency, 80-160 Hz beat frequency, intensity <33 mA) delivering interferential current (2 electrodes over epigastrium + 2 over kidneys) was applied 1 hour daily at home. Continence diaries were kept for 1 month before and 2 months during treatment.

RESULTS

All children completed more than 1 month of treatment after baseline recording. Defecation increased in 9 of 11 children, and soiling decreased in 4 of 11 children. There was a significant increase in total episodes of defecation per week (mean +/- SD, 2.5 +/- 2.1 vs 6.7 +/- 4.4; P = .008) and a nonsignificant decrease in soiling (3.8 +/- 1.6 vs 1.1 +/- 0.5 episodes/wk, P = .1). Daily stimulation does not affect abdominal pain. No adverse events occurred.

CONCLUSIONS

Daily TES at home is safe and significantly improved bowel function in children who did not respond to 3 times per week of TES. Home TES may be a novel treatment of intractable slow transit constipation, avoiding hospital visits.

摘要

目的

经皮电刺激(TES)(每周 3 次)作用于腹部可刺激肠道功能,这在一项随机对照试验中得到了验证。本研究旨在评估在家使用安全、便携的 TES 设备进行每日治疗是否可行,以及其疗效是否优于试验结果。

方法

招募了 11 名(6 名男性/5 名女性;平均年龄 14 岁;范围 12-18 岁)在试验中复发或反应不佳的慢传输型便秘患者(试验后 11 ± 5 个月)。使用 EPM-IF-4160(Fuji Dynamics,Hong Kong)便携式机器(正弦波,4 kHz 载波频率,80-160 Hz 差频,强度<33 mA),在腹部上使用 2 个电极,在肾脏上使用 2 个电极施加干扰电流。在治疗前和治疗期间的 2 个月内,每天在家中应用 1 小时。在治疗前和治疗期间的 1 个月内记录排便情况。

结果

所有患儿在记录基线后均完成了 1 个月以上的治疗。11 名患儿中有 9 名排便次数增加,有 4 名患儿大便失禁减少。每周排便总次数明显增加(平均 ± SD,2.5 ± 2.1 比 6.7 ± 4.4;P =.008),大便失禁次数无显著减少(3.8 ± 1.6 比 1.1 ± 0.5 次/周,P =.1)。每日刺激不影响腹痛。未发生不良事件。

结论

对于每周 3 次 TES 治疗无反应的患儿,家庭 TES 治疗安全且可显著改善肠道功能。家庭 TES 可能是治疗难治性慢传输性便秘的一种新方法,可避免患儿频繁就医。

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