Center for Health Research, Constella Group, Durham, NC, USA.
Ann Epidemiol. 2010 Jan;20(1):23-31. doi: 10.1016/j.annepidem.2009.09.003.
We sought to advance understanding of linkage error in U.S. maternally linked datasets and how the error might affect results of studies based on the linked data.
North Carolina birth and fetal death records for 1988-1997 were maternally linked (n=1,030,029). The maternal set probability, defined as the probability that all records assigned to the same maternal set do in fact represent events to the same woman, was used to assess differential maternal linkage error across race/ethnic groups.
Maternal set probabilities were lower for records specifying Asian or Hispanic race/ethnicity, suggesting greater maternal linkage error for these sets. The lower probabilities for Hispanics were concentrated in women of Mexican origin who were not born in the United States.
Differential linkage error may be a source of bias in studies that use U.S. maternally linked datasets to make comparisons between Hispanics and other groups or among Hispanic subgroups. Methods to quantify and adjust for this potential bias are needed.
我们旨在深入了解美国基于母亲关联数据集中的连锁错误,并探讨这种错误可能如何影响基于关联数据的研究结果。
1988 年至 1997 年,北卡罗来纳州的出生和胎儿死亡记录进行了母亲关联(n=1,030,029)。母体集概率定义为分配给同一母体集的所有记录实际上是否代表同一妇女的事件的概率,用于评估不同种族/族裔群体之间的差异母亲连锁错误。
指定亚洲或西班牙裔种族/族裔的记录的母体集概率较低,表明这些集合的母亲连锁错误更大。西班牙裔的较低概率集中在非美国出生的墨西哥裔女性中。
差异连锁错误可能是使用美国基于母亲关联数据集在西班牙裔和其他群体之间或西班牙裔亚组之间进行比较的研究中的一个偏倚来源。需要定量和调整这种潜在偏差的方法。