Cardiovascular and Respiratory Sciences Department, La Sapienza University, viale del Policlinico 155, Rome, Italy.
Biomed Pharmacother. 2010 Mar;64(3):177-83. doi: 10.1016/j.biopha.2009.09.017. Epub 2009 Nov 18.
Histologic and ultrastructural examination of atrial tissue regarding the main entities responsible of human atrial fibrillation, is reported. The pathologic changes deriving from various disorders, like degenerative, inflammatory, ischemic diseases as well as from cardiac aging and hormonal imbalance are analysed. Structural changes associated with lone atrial fibrillation and investigated by atrial biopsy are also described, as being able to provide useful information on the disease's etiology, prognosis and treatment.
本文报道了人类心房颤动主要相关实体的心房组织的组织学和超微结构检查。分析了源自各种疾病（如退行性、炎症性、缺血性疾病以及心脏老化和激素失衡）的病理变化。还描述了与孤立性心房颤动相关的结构变化，并通过心房活检进行了研究，因为它能够提供有关疾病病因、预后和治疗的有用信息。
