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中枢神经系统表面铁沉积症表现为癫痫发作。

Superficial siderosis of the central nervous system manifested with seizures.

机构信息

Department of Neurology, The First Affiliated Hospital, School of Medicine, Zhejiang University, ZheJiang Province 310003, China.

出版信息

J Clin Neurosci. 2010 Feb;17(2):277-8. doi: 10.1016/j.jocn.2009.04.016. Epub 2009 Dec 16.

Abstract

Superficial siderosis of the central nervous system (CNS) is caused by repeated hemorrhage into the subarachnoid space with resultant hemosiderin deposition in the subpial layers of the brain and spinal cord. Progressive ataxia and hearing impairment are the most common manifestations of the disorder. We describe a male patient admitted to our hospital for recurrent seizures over the past 3 months. He was diagnosed eventually as having superficial siderosis of the CNS through brain MRI; however, he presented with only mild hearing impairment without any cerebellar deficits. Seizures can be the major presentation of the superficial siderosis.

摘要

中枢神经系统(CNS)表面铁沉积症是由于蛛网膜下腔反复出血,导致脑和脊髓软膜下层含铁血黄素沉积所致。进行性共济失调和听力障碍是该病最常见的表现。我们描述了一名男性患者,他因过去 3 个月反复发作性癫痫而入院。最终通过脑部 MRI 诊断为 CNS 表面铁沉积症,但他仅表现为轻度听力障碍,而无小脑功能缺损。癫痫发作可能是 CNS 表面铁沉积症的主要表现。

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