Rush University Medical Center, 1725 W. Harrison St. #970, Chicago, IL 60612, USA.
Spine J. 2010 Feb;10(2):e1-4. doi: 10.1016/j.spinee.2009.10.016. Epub 2009 Dec 16.
Infuse [bone morphogenetic protein (BMP)] is increasingly used in spinal fusion surgery.
The authors report a rare complication of BMP use.
This is a case report.
A 55-year-old male underwent a thoracic T8 to the pelvis fusion for degenerative lumbar disc disease and pseudarthrosis at another institution. The procedure involved an anterior and posterior approach with the use of multiple units of BMP.
The patient presented to our institution with complaints of weight loss, pain, tenderness, and increasing solid growth in the left lower quadrant several months after his surgery. A computed tomography revealed ectopic bone growth in the retroperitoneal area and pelvis contiguous to the anterior lumbar exposure.
The anterior wound was re-explored, and a large sheet of ectopic bone was removed from the retroperitoneal space.
We report a rare case of extraspinal ectopic bone growth because of the use of multiple packages of BMP.
在脊柱融合手术中，[骨形态发生蛋白（BMP）]的应用越来越多。
作者报告了 BMP 使用的一种罕见并发症。
这是一个病例报告。
一名 55 岁男性因退行性腰椎间盘疾病和另一家机构的假关节在 T8 胸椎至骨盆融合。该手术采用前路和后路入路，使用了多个单位的 BMP。
该患者在手术后几个月出现左侧下象限体重减轻、疼痛、压痛和不断增大的实性生长的症状，来我院就诊。计算机断层扫描显示腹膜后和与前路腰椎暴露相邻的骨盆部位有异位骨生长。
重新探查前路伤口，从腹膜后空间取出一大片异位骨。
我们报告了一例罕见的脊柱外异位骨生长病例，这是由于使用了多包 BMP。
