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伤口性肉毒中毒，复杂性桡骨骨折内固定术后。

Wound botulism complicating internal fixation of a complex radial fracture.

机构信息

Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Clin Microbiol. 2010 Feb;48(2):650-3. doi: 10.1128/JCM.01258-09. Epub 2009 Dec 9.

DOI:10.1128/JCM.01258-09
PMID:20007390
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2815637/
Abstract

Botulism developed in a patient following surgical repair of an open radial fracture. Symptoms resolved after treatment with antitoxin and antibiotics, and hardware excision was deferred. Subsequent osteomyelitis necessitated hardware exchange, and wound cultures grew Clostridium argentinense. This case highlights the management of botulism associated with orthopedic hardware.

摘要

患者在接受开放性桡骨骨折手术后出现了肉毒中毒。经过抗毒素和抗生素治疗后，症状得到缓解，且推迟了硬件切除。随后发生的骨髓炎需要更换硬件，伤口培养出了阿根廷梭菌。本病例强调了与骨科硬件相关的肉毒中毒的处理。

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本文引用的文献

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Phylogenetic analysis of viridans group streptococci causing endocarditis.引起心内膜炎的草绿色链球菌的系统发育分析。
J Clin Microbiol. 2008 Sep;46(9):3087-90. doi: 10.1128/JCM.00920-08. Epub 2008 Jul 23.
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Wound botulism in California, 1951-1998: recent epidemic in heroin injectors.1951 - 1998年加利福尼亚州的创伤性肉毒中毒：海洛因注射者中的近期流行情况
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3
Nucleotide sequence of the gene coding for Clostridium botulinum (Clostridium argentinense) type G neurotoxin: genealogical comparison with other clostridial neurotoxins.编码肉毒梭菌（阿根廷肉毒梭菌）G型神经毒素的基因的核苷酸序列：与其他梭菌神经毒素的谱系比较。
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Detection of type A, B, and E botulism neurotoxin genes in Clostridium botulinum and other Clostridium species by PCR: evidence of unexpressed type B toxin genes in type A toxigenic organisms.
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Response and immunoresistance to botulinum toxin injections.对肉毒杆菌毒素注射的反应及免疫抵抗
Neurology. 1995 Sep;45(9):1743-6. doi: 10.1212/wnl.45.9.1743.
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Antibiotic effects on bacterial viability, toxin production, and host response.抗生素对细菌活力、毒素产生及宿主反应的影响。
Clin Infect Dis. 1995 Jun;20 Suppl 2:S154-7. doi: 10.1093/clinids/20.supplement_2.s154.
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Isolation of Clostridium botulinum type G and identification of type G botulinal toxin in humans: report of five sudden unexpected deaths.G型肉毒梭菌的分离及人体中G型肉毒毒素的鉴定：五例意外猝死报告
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Susceptibility of Clostridium botulinum to thirteen antimicrobial agents.肉毒梭菌对13种抗菌剂的敏感性
Antimicrob Agents Chemother. 1980 Jul;18(1):13-9. doi: 10.1128/AAC.18.1.13.
9
Antitoxin levels in botulism patients treated with trivalent equine botulism antitoxin to toxin types A, B, and E.接受针对A、B和E型毒素的三价马源肉毒中毒抗毒素治疗的肉毒中毒患者的抗毒素水平。
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10
Another type of Clostridium botulinum.另一种肉毒梭菌。
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