DaVita Inc., Lakewood, Colorado, USA.
Clin J Am Soc Nephrol. 2010 Feb;5(2):248-51. doi: 10.2215/CJN.03700609. Epub 2009 Dec 10.
The association between level of performance in achieving guideline-recommended clinical indicators and relative reduction in patient mortality is inconsistent among large dialysis organizations (LDOs). Because growth rates among providers differ, we reasoned that clinical performance and mortality rates in dialysis facilities may be related to length of facility ownership.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined achievement of clinical performance indicators among prevalent long-term hemodialysis patients who were enrolled in cohorts of DaVita facilities between December 2005 and December 2007. We compared results in 606 facilities owned before December 1, 2004 (existing), with those seen in 504 facilities that were acquired in October 2005 (newly acquired).
At baseline, existing compared with newly acquired DaVita facilities showed higher levels of clinical performance and lower patient mortality. These differences persisted up to 2 years for selected outcomes, including dialysis adequacy and anemia management. Substantial improvement was seen in both cohorts for mineral bone disease outcomes; however, 2 years after acquisition, between-cohort differences in relative risk for death were no longer discernible.
These findings confirm that intervention to improve quality outcomes in dialysis facilities produces direct benefits that are tangible to patients. Our results also provide new evidence that length of ownership may be a significant factor in determining facility performance within a large dialysis organization.
在大型透析机构(LDO)中,达到指南推荐的临床指标水平与患者死亡率相对降低之间的关联并不一致。由于提供者的增长率不同,我们推测透析设施的临床绩效和死亡率可能与设施拥有时间的长短有关。
设计、环境、参与者和测量:我们检查了在 2005 年 12 月至 2007 年 12 月期间参加 DaVita 设施队列的普遍长期血液透析患者中临床绩效指标的实现情况。我们将 2004 年 12 月 1 日前(现有)拥有的 606 个设施的结果与 2005 年 10 月收购的 504 个新收购设施的结果进行了比较。
在基线时,与新收购的 DaVita 设施相比,现有的 DaVita 设施显示出更高的临床绩效和更低的患者死亡率。这些差异在选定的结果中持续了 2 年,包括透析充分性和贫血管理。两个队列的矿物质骨疾病结果都有显著改善;然而,在收购后 2 年,死亡相对风险的队列间差异不再明显。
这些发现证实,干预措施可改善透析设施的质量结果,为患者带来切实可见的益处。我们的研究结果还提供了新的证据,表明在大型透析组织内,拥有时间的长短可能是决定设施绩效的一个重要因素。