DaVita Clinical Research, Minneapolis, MN 55404, USA.
Am J Kidney Dis. 2012 Sep;60(3):435-43. doi: 10.1053/j.ajkd.2012.04.009. Epub 2012 May 17.
Patients beginning dialysis therapy are at risk of death and illness. The IMPACT (Incident Management of Patients, Actions Centered on Treatment) quality improvement program was developed to improve incident hemodialysis patient outcomes through standardized care.
Quality improvement report.
SETTING & PARTICIPANTS: Patients who started hemodialysis therapy between September 2007 and December 2008 at DaVita facilities using the IMPACT program (n = 1,212) constituted the intervention group. Propensity score-matched patients who initiated hemodialysis therapy in the same interval at DaVita facilities not using the IMPACT program (n = 2,424) made up the control group.
IMPACT intervention included a structured intake process and monitoring reports; patient enrollment in a 90-day patient education program and 90-day patient management pathway.
Mean dialysis adequacy (Kt/V), hemoglobin and albumin levels, percentage of patients using preferred vascular access (arteriovenous fistula or graft), and mortality at each quarter.
Compared with the non-IMPACT group, the IMPACT group was associated with a higher proportion of patients dialyzing with a preferred access at 90 days (0.50 [95% CI, 0.47-0.53] vs 0.47 [95% CI, 0.45-0.49]; P = 0.1) and 360 days (0.63 [95% CI, 0.61-0.66] vs 0.48 [95% CI, 0.46-0.50]; P < 0.001) and a lower mortality rate at 90 days (24.8 [95% CI, 19.0-30.7] vs 31.9 [95% CI, 27.1-36.6] deaths/100 patient-years; P = 0.08) and 360 days (17.8 [95% CI, 15.2-20.4] vs 25.1 [95% CI, 20.7-25.2] deaths/100 patient-years; P = 0.01).
The study does not determine the care processes responsible for the improved outcomes.
Intense management of incident dialysis patients with the IMPACT quality improvement program was associated with significantly decreased first-year mortality. Focused attention to the care of incident patients is an important part of a dialysis program.
开始透析治疗的患者有死亡和患病的风险。IMPACT(患者事件管理,以治疗为中心的行动)质量改进计划旨在通过标准化护理改善事件性血液透析患者的结局。
质量改进报告。
在 DaVita 设施中,2007 年 9 月至 2008 年 12 月期间开始血液透析治疗的患者(n=1212)构成干预组。在 DaVita 设施中,在同一时间段内开始血液透析治疗但未使用 IMPACT 计划的患者(n=2424)经倾向评分匹配构成对照组。
IMPACT 干预包括结构化的摄入流程和监测报告;患者参加 90 天患者教育计划和 90 天患者管理途径。
每季度的平均透析充分性(Kt/V)、血红蛋白和白蛋白水平、使用首选血管通路(动静脉瘘或移植物)的患者比例和死亡率。
与非 IMPACT 组相比,IMPACT 组在 90 天(0.50[95%CI,0.47-0.53]vs0.47[95%CI,0.45-0.49];P=0.1)和 360 天(0.63[95%CI,0.61-0.66]vs0.48[95%CI,0.46-0.50];P<0.001)时使用首选通路的患者比例更高,90 天死亡率较低(24.8[95%CI,19.0-30.7]vs31.9[95%CI,27.1-36.6]死亡/100 患者年;P=0.08)和 360 天(17.8[95%CI,15.2-20.4]vs25.1[95%CI,20.7-25.2]死亡/100 患者年;P=0.01)。
该研究未确定导致改善结果的护理过程。
使用 IMPACT 质量改进计划对新发生的透析患者进行强化管理,与第一年死亡率显著降低相关。关注新发生的患者的护理是透析计划的重要组成部分。