Department of Anesthesiology PH 527-B, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, NY 10032, USA.
Br J Anaesth. 2009 Dec;103 Suppl 1:i57-65. doi: 10.1093/bja/aep271.
The incidence of asthma is increasing worldwide, but morbidity and mortality are decreasing because of improvements in medical care. Although the incidence of severe perioperative bronchospasm is relatively low in asthmatics undergoing anaesthesia, when it does occur it may be life-threatening. The keys to an uncomplicated perioperative course are assiduous attention to detail in preoperative assessment, and maintenance of the anti-inflammatory and bronchodilatory regimens through the perioperative period. Potential trigger agents should be identified and avoided. Many routinely used anaesthetic agents have an ameliorative effect on airway constriction. Nonetheless, acute bronchospasm can still occur, especially at induction and emergence, and should be promptly and methodically managed.
哮喘的发病率在全球范围内呈上升趋势,但由于医疗水平的提高,发病率和死亡率正在下降。尽管在接受麻醉的哮喘患者中,严重围手术期支气管痉挛的发生率相对较低,但当它发生时,可能会危及生命。围手术期无并发症的关键是在术前评估中细致入微地关注细节,并通过围手术期维持抗炎和支气管扩张治疗方案。应识别并避免潜在的触发因素。许多常用的麻醉剂对气道收缩有改善作用。尽管如此,急性支气管痉挛仍可能发生,尤其是在诱导和苏醒时,应及时、系统地进行管理。