University Hospital, Ancona, Italy.
Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3 Suppl):S83-90. doi: 10.1177/03946320110240s312.
The incidence of asthma is increasing worldwide, but morbidity and mortality are decreasing, because of improvements in medical care. Although the incidence of severe perioperative bronchospasm is relatively low in asthmatics undergoing anaesthesia, when it does occur it may be life-threatening. Preoperative assessment of asthma should include a specialized medical hystory and physical examination as well as pulmonary function testing. Potential trigger agents should be identified and avoided. In many asthmatic patients treatment with systemic corticosteroids and bronchodilators is indicated to prevent the inflammation and bronchocostriction associated with endotracheal intubation. Nonetheless, acute bronchospasm can still occur, especially at induction and emergence, and should be promptly and methodically managed.
哮喘的发病率在全球范围内呈上升趋势,但由于医疗水平的提高,发病率和死亡率呈下降趋势。尽管在接受麻醉的哮喘患者中,严重围手术期支气管痉挛的发生率相对较低,但如果发生,可能会危及生命。哮喘的术前评估应包括专门的病史和体格检查以及肺功能测试。应识别并避免潜在的触发因素。在许多哮喘患者中,需要使用全身皮质激素和支气管扩张剂进行治疗,以预防与气管内插管相关的炎症和支气管收缩。尽管如此,急性支气管痉挛仍可能发生,尤其是在诱导和苏醒期间,应及时、有条不紊地进行处理。