Department of Psychiatry and Behavioral Sciences, Healthy Childhood Brain Development Developmental Traumatology Research Program, Duke University Medical Center, Durham, NC 27710, USA.
J Pediatr Psychol. 2010 Jun;35(5):570-7. doi: 10.1093/jpepsy/jsp116. Epub 2009 Dec 11.
To examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms.
Participants included 216 children with maltreatment histories (N = 49), maltreatment and PTSD (N = 49), or no maltreatment (N = 118). Participants received diagnostic interviews, brain imaging, and neuropsychological evaluations.
We examined a hierarchical regression model comprised of independent variables including demographics, trauma and maltreatment-related variables, and hippocampal volumes and neuropsychological measures to model PTSD symptoms. Important independent contributors to this model were SES, and General Maltreatment and Sexual Abuse Factors. Although hippocampal volumes were not significant, Visual Memory was a significant contributor to this model.
Similar to adult PTSD, pediatric PTSD symptoms are associated with lower Visual Memory performance. It is an important correlate of PTSD beyond established predictors of PTSD symptoms. These results support models of developmental traumatology and suggest that treatments which enhance visual memory may decrease symptoms of PTSD.
探讨人口统计学、虐待、神经结构和神经心理学测量与创伤后应激障碍（ PTSD ）总症状的关系。
参与者包括 216 名有虐待史的儿童（ N = 49）、虐待和 PTSD （ N = 49）或无虐待（ N = 118）。参与者接受了诊断访谈、脑成像和神经心理学评估。
我们检验了一个由人口统计学、创伤和虐待相关变量以及海马体积和神经心理学测量组成的分层回归模型，以预测 PTSD 症状。该模型的重要独立贡献者是 SES 和一般虐待因素以及性虐待因素。虽然海马体积不显著，但视觉记忆是该模型的重要贡献者。
与成人 PTSD 相似，儿科 PTSD 症状与较低的视觉记忆表现相关。它是 PTSD 的一个重要相关因素，超过了 PTSD 症状的既定预测因素。这些结果支持发展性创伤学模型，并表明增强视觉记忆的治疗方法可能会降低 PTSD 症状。
