NANOS：生殖干细胞的守护天使。
NANOS: a germline stem cell's Guardian Angel.
机构信息
Stowers Institute for Medical Research, Kansas City, MO 64110, USA.
出版信息
J Mol Cell Biol. 2010 Apr;2(2):76-7. doi: 10.1093/jmcb/mjp043. Epub 2009 Dec 11.
PMID:20008335
Abstract
NANOS is known to be required for germline cell development in a variety of animal species and for the maintenance of germline stem cells in Drosophila. The recent study by Sada et al. has demonstrated that NANOS2, one of the three mammalian homologues, is required intrinsically for maintaining adult mouse spermatogonial stem cell self-renewal.
摘要
NANOS 已知在多种动物物种的生殖细胞发育和果蝇生殖干细胞的维持中是必需的。最近 Sada 等人的研究表明，三种哺乳动物同源物之一的 NANOS2 内在地需要维持成年小鼠精原干细胞的自我更新。
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