Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92037, USA.
J Cell Biol. 2009 Dec 14;187(6):757-9. doi: 10.1083/jcb.200911084.
Division plane specification in animal cells has long been presumed to involve direct contact between microtubules of the anaphase mitotic spindle and the cell cortex. In this issue, von Dassow et al. (von Dassow et al. 2009. J. Cell. Biol. doi:10.1083/jcb.200907090) challenge this assumption by showing that spindle microtubules can effectively position the division plane at a distance from the cell cortex.
在动物细胞中,分裂面的确定长期以来一直被认为涉及后期有丝分裂纺锤体的微管与细胞质膜之间的直接接触。在本期杂志中,von Dassow 等人(von Dassow 等人,2009 年,《细胞生物学杂志》。doi:10.1083/jcb.200907090)通过表明纺锤体微管可以有效地将分裂面定位在远离细胞质膜的位置,对这一假设提出了挑战。