• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Electrophysiological challenges of cell-based myocardial repair.

作者信息

Chen Huei-Sheng Vincent, Kim Changsung, Mercola Mark

机构信息

Burnham Institute for Medical Research, 10901 N Torrey Pines Rd, La Jolla, CA 92037, USA.

出版信息

Circulation. 2009 Dec 15;120(24):2496-508. doi: 10.1161/CIRCULATIONAHA.107.751412.

DOI:10.1161/CIRCULATIONAHA.107.751412
PMID:20008740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3293934/
Abstract
摘要

相似文献

1
Electrophysiological challenges of cell-based myocardial repair.基于细胞的心肌修复的电生理挑战。
Circulation. 2009 Dec 15;120(24):2496-508. doi: 10.1161/CIRCULATIONAHA.107.751412.
2
Potential Strategies for Clinical Translation of Repeated Cell Therapy.重复细胞治疗的临床转化的潜在策略。
Circ Res. 2019 Mar;124(5):690-692. doi: 10.1161/CIRCRESAHA.118.314653.
3
Cardiomyocyte maturation: It takes a village to raise a kid.心肌细胞成熟:养育一个孩子需要众人相助。
J Mol Cell Cardiol. 2014 Sep;74:193-5. doi: 10.1016/j.yjmcc.2014.05.012. Epub 2014 May 27.
4
Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies.遗传性心肌病中的诱导多能干细胞:从疾病机制到新疗法。
Trends Cardiovasc Med. 2016 Nov;26(8):663-672. doi: 10.1016/j.tcm.2016.05.001. Epub 2016 May 11.
5
Regenerative Therapy for Cardiomyopathies.心肌疾病的再生治疗。
J Cardiovasc Transl Res. 2018 Oct;11(5):357-365. doi: 10.1007/s12265-018-9807-z. Epub 2018 May 9.
6
Pluripotent stem cell-derived cardiomyocytes for treatment of cardiomyopathic damage: Current concepts and future directions.用于治疗心肌病损伤的多能干细胞衍生心肌细胞:当前概念与未来方向
Trends Cardiovasc Med. 2021 Feb;31(2):85-90. doi: 10.1016/j.tcm.2020.01.002. Epub 2020 Jan 14.
7
Human stem cells shape the future of cardiac regeneration research.人类干细胞塑造了心脏再生研究的未来。
Int J Cardiol. 2004 Jun;95 Suppl 1:S20-2. doi: 10.1016/s0167-5273(04)90006-x.
8
Donor cell transplantation for myocardial disease: does it complement current pharmacological therapies?用于心肌病的供体细胞移植:它是否能补充当前的药物治疗?
Can J Physiol Pharmacol. 2007 Jan;85(1):1-15. doi: 10.1139/Y06-105.
9
Stem cell experiments and initial clinical trial of cellular cardiomyoplasty.干细胞实验与细胞心肌成形术的初步临床试验。
Asian Cardiovasc Thorac Ann. 2009 Dec;17(6):581-6. doi: 10.1177/0218492309349363.
10
Cardiac regeneration and stem cell therapy.心脏再生与干细胞治疗。
Curr Opin Organ Transplant. 2008 Oct;13(5):536-42. doi: 10.1097/MOT.0b013e32830fdfc4.

引用本文的文献

1
Metabolic Culture Medium Enhances Maturation of Human iPSC-Derived Cardiomyocytes via Cardiac Troponin I Isoform Induction.代谢培养基通过诱导心肌肌钙蛋白I亚型增强人诱导多能干细胞衍生心肌细胞的成熟。
Int J Mol Sci. 2025 Jul 26;26(15):7248. doi: 10.3390/ijms26157248.
2
Induced Pluripotent Stem Cells in Cardiomyopathy: Advancing Disease Modeling, Therapeutic Development, and Regenerative Therapy.诱导多能干细胞在心肌病中的应用:推动疾病建模、治疗开发和再生治疗
Int J Mol Sci. 2025 May 22;26(11):4984. doi: 10.3390/ijms26114984.
3
hiPSC-derived cardiac fibroblasts dynamically enhance the mechanical function of hiPSC-derived cardiomyocytes on an engineered substrate.

本文引用的文献

1
TGF-beta1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro.转化生长因子-β1在体外诱导人心脏祖细胞高效分化为功能性心肌细胞。
Stem Cell Res. 2007 Nov;1(2):138-49. doi: 10.1016/j.scr.2008.02.003. Epub 2008 Mar 12.
2
Promise of blood- and bone marrow-derived stem cell transplantation for functional cardiac repair: putting it in perspective with existing therapy.血液和骨髓来源的干细胞移植用于功能性心脏修复的前景:与现有疗法对比分析
J Am Coll Cardiol. 2009 Jan 27;53(4):305-8. doi: 10.1016/j.jacc.2008.10.018.
3
Paracrine mechanisms in adult stem cell signaling and therapy.
人诱导多能干细胞来源的心脏成纤维细胞在工程化基质上动态增强人诱导多能干细胞来源的心肌细胞的机械功能。
Front Bioeng Biotechnol. 2025 May 23;13:1546483. doi: 10.3389/fbioe.2025.1546483. eCollection 2025.
4
Advancements in techniques for human iPSC-derived cardiomyocytes maturation: mechanical and electrical stimulation approaches.人诱导多能干细胞衍生心肌细胞成熟技术的进展:机械和电刺激方法。
Biophys Rev. 2025 Jan 3;17(1):169-183. doi: 10.1007/s12551-024-01267-6. eCollection 2025 Feb.
5
Ascorbic acid induces MLC2v protein expression and promotes ventricular-like cardiomyocyte subtype in human induced pluripotent stem cells derived cardiomyocytes.抗坏血酸诱导 MLC2v 蛋白表达并促进人诱导多能干细胞衍生的心肌细胞向心室样心肌细胞亚型分化。
Theranostics. 2023 Jul 3;13(11):3872-3896. doi: 10.7150/thno.80801. eCollection 2023.
6
Gene-Edited Human-Induced Pluripotent Stem Cell Lines to Elucidate Function throughout Cardiac Differentiation.基因编辑的人类诱导多能干细胞系,以阐明心脏分化过程中的功能。
Cells. 2023 Feb 5;12(4):520. doi: 10.3390/cells12040520.
7
Three-Dimensional Bio-Printed Cardiac Patch for Sustained Delivery of Extracellular Vesicles from the Interface.用于从界面持续递送细胞外囊泡的三维生物打印心脏补片
Gels. 2022 Nov 25;8(12):769. doi: 10.3390/gels8120769.
8
Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair.基于细胞重编程的心脏再生修复方法的研究进展。
Cells. 2022 Dec 3;11(23):3914. doi: 10.3390/cells11233914.
9
Human Induced Pluripotent Stem Cell Encapsulation Geometry Impacts Three-Dimensional Developing Human Engineered Cardiac Tissue Functionality.人诱导多能干细胞包封几何形状影响三维发育的人源工程心脏组织功能。
Tissue Eng Part A. 2022 Dec;28(23-24):990-1000. doi: 10.1089/ten.TEA.2022.0107.
10
Transient secretion of VEGF protein from transplanted hiPSC-CMs enhances engraftment and improves rat heart function post MI.移植的 hiPSC-CMs 短暂分泌 VEGF 蛋白可增强植入物并改善 MI 后大鼠心功能。
Mol Ther. 2023 Jan 4;31(1):211-229. doi: 10.1016/j.ymthe.2022.08.012. Epub 2022 Aug 17.
成体干细胞信号传导与治疗中的旁分泌机制。
Circ Res. 2008 Nov 21;103(11):1204-19. doi: 10.1161/CIRCRESAHA.108.176826.
4
Get with the (re)program: cardiovascular potential of skin-derived induced pluripotent stem cells.跟上(重新)编程的步伐:皮肤来源的诱导多能干细胞的心血管潜力。
Circulation. 2008 Jul 29;118(5):472-5. doi: 10.1161/CIRCULATIONAHA.108.791442.
5
Cardiovascular regenerative medicine: digging in for the long haul.心血管再生医学:进行长期钻研。
Cell Stem Cell. 2007 Dec 13;1(6):628-33. doi: 10.1016/j.stem.2007.11.011.
6
The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation.缺血性心肌病成肌细胞自体移植(MAGIC)试验:成肌细胞移植的首个随机安慰剂对照研究。
Circulation. 2008 Mar 4;117(9):1189-200. doi: 10.1161/CIRCULATIONAHA.107.734103. Epub 2008 Feb 19.
7
Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart.灌注脱细胞基质:利用自然平台构建生物人工心脏
Nat Med. 2008 Feb;14(2):213-21. doi: 10.1038/nm1684. Epub 2008 Jan 13.
8
The real estate of myoblast cardiac transplantation: negative remodeling is associated with location.成肌细胞心脏移植的转归:负性重塑与移植部位相关。
J Heart Lung Transplant. 2008 Jan;27(1):116-23. doi: 10.1016/j.healun.2007.10.011.
9
Clinical trials update from the American Heart Association 2007: CORONA, RethinQ, MASCOT, AF-CHF, HART, MASTER, POISE and stem cell therapy.美国心脏协会2007年临床试验更新:CORONA、RethinQ、MASCOT、AF-CHF、HART、MASTER、POISE及干细胞疗法。
Eur J Heart Fail. 2008 Jan;10(1):102-8. doi: 10.1016/j.ejheart.2007.12.004.
10
The multifaceted role of Notch in cardiac development and disease.Notch在心脏发育和疾病中的多方面作用。
Nat Rev Genet. 2008 Jan;9(1):49-61. doi: 10.1038/nrg2279.