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遗传性出血性黄斑营养不良。

Hereditary hemorrhagic macular dystrophy.

作者信息

Wu G, Pruett R C, Baldinger J, Hirose T

机构信息

Retina Associates, Boston, Massachusetts 02114.

出版信息

Am J Ophthalmol. 1991 Mar 15;111(3):294-301. doi: 10.1016/s0002-9394(14)72312-8.

DOI:10.1016/s0002-9394(14)72312-8
PMID:2000899
Abstract

We treated two brothers who had a hemorrhagic macular lesion in one eye; a similar problem affected the fellow eye of both patients within eight months. Generalized fine granularity of the retinal pigment epithelium and peripheral iris transillumination defects were observed in both siblings. A study of the family suggested that the disorder was dominantly inherited and probably was Sorsby's pseudoinflammatory macular dystrophy. The macular lesions in one brother were treated by argon green laser photocoagulation and in the other brother by krypton red laser photocoagulation. Although the brother treated by krypton red laser photocoagulation attained better final visual function, additional differences in treatment methods also may have contributed to the final outcome.

摘要

我们治疗了两名兄弟,他们其中一只眼睛患有出血性黄斑病变;在八个月内,类似问题影响了两名患者的另一只眼睛。在两名患者中均观察到视网膜色素上皮的普遍细微颗粒状改变以及周边虹膜透照缺损。对该家族的一项研究表明,这种病症为显性遗传,可能是索斯比假性炎症性黄斑营养不良。其中一名兄弟的黄斑病变采用氩绿激光光凝治疗,另一名兄弟则采用氪红激光光凝治疗。尽管接受氪红激光光凝治疗的兄弟最终获得了更好的视力功能,但治疗方法的其他差异也可能对最终结果产生了影响。

相似文献

1
Hereditary hemorrhagic macular dystrophy.遗传性出血性黄斑营养不良。
Am J Ophthalmol. 1991 Mar 15;111(3):294-301. doi: 10.1016/s0002-9394(14)72312-8.
2
Pseudoinflammatory macular dystrophy.假性炎症性黄斑营养不良
Trans Am Ophthalmol Soc. 1977;75:255-71.
3
Pseudoinflammatory macular dystrophy.假性炎症性黄斑营养不良
Am J Ophthalmol. 1988 Aug 15;106(2):154-61. doi: 10.1016/0002-9394(88)90827-6.
4
Sorsby's fundus dystrophy.索斯比眼底营养不良症
Ophthalmology. 1989 Dec;96(12):1755-62. doi: 10.1016/s0161-6420(89)32647-9.
5
Sorsby's fundus dystrophy in a family with a Ser-181-CVS mutation in the TIMP-3 gene: poor outcome after laser photocoagulation.
Trans Am Ophthalmol Soc. 1996;94:275-94; discussion 295-7.
6
Fenestrated sheen macular dystrophy.
Am J Ophthalmol. 1991 Jul 15;112(1):1-7. doi: 10.1016/s0002-9394(14)76204-x.
7
Hereditary hemorrhagic macular dystrophy.
Am J Ophthalmol. 1978 Mar;85(3):318-28. doi: 10.1016/s0002-9394(14)77722-0.
8
Comparisons of photocoagulation treatment in exudative age-related macular degeneration with the blue-green argon, green argon and red krypton laser wavelengths.采用蓝绿氩激光、绿氩激光和红氪激光波长对渗出性年龄相关性黄斑变性进行光凝治疗的比较。
Ophthalmologica. 1993;207(1):46-54. doi: 10.1159/000310405.
9
[Sorsby's pseudo-inflammatory macular dystrophy: laser treatment].
J Fr Ophtalmol. 1989;12(12):863-8.
10
Indocyanine green angiography in Sorsby's fundus dystrophy.
Graefes Arch Clin Exp Ophthalmol. 2000 Feb;238(2):158-62. doi: 10.1007/pl00007885.

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Sorsby's fundus dystrophy in a family with a Ser-181-CVS mutation in the TIMP-3 gene: poor outcome after laser photocoagulation.
Trans Am Ophthalmol Soc. 1996;94:275-94; discussion 295-7.