Shan Guo-Dong, Xu Guo-Qiang, Chen Li-Hua, Wang Zhao-Ming, Jin En-Yun, Hu Feng-Ling, Li You-Ming
Department of Gastroenterology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Intern Med. 2009;48(24):2093-6. doi: 10.2169/internalmedicine.48.2542.
Diffuse liver infiltration by melanoma of unknown primary origin is rare. We encountered a unique case of diffuse liver infiltration by melanoma of unknown primary origin in our hospital. A 62-year-old woman was referred to our hospital for anorexia of 6 months duration and abdominal distension for 1 month. Ultrasonography (US), computerized tomography (CT) and magnetic resonance imaging (MRI) revealed an obvious enlarged liver without detectable nodules. She was diagnosed as liver metastasis by melanoma of unknown primary origin via percutaneous liver biopsy. The report demonstrates the difficulty of making a noninvasive diagnosis of diffuse hepatic infiltration on metastatic melanoma.
原发性不明的黑色素瘤弥漫性肝浸润很少见。我院遇到一例原发性不明的黑色素瘤弥漫性肝浸润的独特病例。一名62岁女性因持续6个月的厌食和1个月的腹胀被转诊至我院。超声（US）、计算机断层扫描（CT）和磁共振成像（MRI）显示肝脏明显肿大，未发现结节。经皮肝活检诊断为原发性不明的黑色素瘤肝转移。该报告显示了对转移性黑色素瘤弥漫性肝浸润进行无创诊断的困难。
