MORITA Rena, HASHINO Satoshi, OKADA Kohei, TAKAHATA Mutsumi, ONOZAWA Masahiro, KAHATA Kaoru, KONDO Takeshi, IMAMURA Masahiro, ASAKA Masahiro
Department of Gastroenterology and Hematology, Hokkaido University Graduate School of Medicine.
Rinsho Ketsueki. 2009 Nov;50(11):1655-7.
A 53-year-old woman had demonstrated idiopathic thrombocytopenic purpura (ITP) and iron deficiency anemia (IDA) since 1978. Although she was treated with prednisolone for ITP and oral iron compounds for IDA, neither ITP nor IDA showed any improvement. Since her (13)C-urea breath test was positive, Helicobacter pylori (H. pylori) eradication therapy was performed in 2001. The therapy was effective for IDA but not for ITP. Analysis of cases such as this will be useful for clarifying the mechanisms underlying the development of ITP and IDA associated with H. pylori.
一名53岁女性自1978年起患有特发性血小板减少性紫癜(ITP)和缺铁性贫血(IDA)。尽管她接受了泼尼松龙治疗ITP以及口服铁剂治疗IDA,但ITP和IDA均未见任何改善。由于她的碳-13尿素呼气试验呈阳性,2001年进行了幽门螺杆菌(H. pylori)根除治疗。该治疗对IDA有效,但对ITP无效。分析此类病例将有助于阐明与幽门螺杆菌相关的ITP和IDA发生发展的潜在机制。