Division of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Duke University Hospital, Durham, NC 27710, USA.
Plast Reconstr Surg. 2010 Mar;125(3):924-34. doi: 10.1097/PRS.0b013e3181cc9630.
Free tissue transfer to the lower extremity has become a well-established reconstructive modality. The purpose of this study was to develop a "subunit" approach to patients undergoing free tissue transfer for foot and ankle wounds to help further define subunit-specific functional and aesthetic operative goals.
The institutional review board approved this retrospective review of 161 patients who underwent free tissue transplantation for foot and ankle wounds between March 1, 1997, and February 28, 2007, at a single institution. Endpoints included flap-related complications, secondary surgery, time to ambulation, flap stability, and limb salvage.
The most common types of wounds treated were trauma-related [n = 120 (75 percent)], diabetes-related [n = 24 (15 percent)], and oncologic defects [n = 8 (5 percent)]. Ten different donor sites were used for reconstruction, with the latissimus dorsi flap being the most common. The mean follow-up time was 26.9 months (range, 0.5 to 130 months). Mean time to ambulation was 3.1 months (range, 0.75 to 14 months). Overall, 11 percent of patients required revision surgery for flap instability at a mean time of 25.3 months after flap surgery. Wounds located over the heel (subunit 5) were most likely to develop instability (Fisher's exact test, p < 0.05). The overall 5-year limb salvage rate as determined by Kaplan-Meier analysis was 89 percent.
The use of free tissue transplantation for treatment of foot and ankle wounds is associated with a high rate of limb salvage. Although a variety of flaps may be used, the application of the subunit principle can assist surgeons in designing flaps that will address subunit-specific functional and aesthetic concerns.
游离组织移植已成为一种成熟的重建方法。本研究的目的是为接受游离组织移植治疗足部和踝关节伤口的患者开发一种“亚单位”方法,以帮助进一步明确亚单位特定的功能和美学手术目标。
本机构审查委员会批准了对 161 名患者的回顾性研究,这些患者于 1997 年 3 月 1 日至 2007 年 2 月 28 日在一家医疗机构接受游离组织移植治疗足部和踝关节伤口。研究终点包括皮瓣相关并发症、二次手术、开始行走的时间、皮瓣稳定性和肢体保留。
最常见的治疗伤口类型为创伤相关[120 例(75%)]、糖尿病相关[24 例(15%)]和肿瘤相关缺陷[8 例(5%)]。10 种不同的供区用于重建,其中最常用的是背阔肌皮瓣。平均随访时间为 26.9 个月(范围,0.5 至 130 个月)。开始行走的平均时间为 3.1 个月(范围,0.75 至 14 个月)。总体而言,11%的患者在皮瓣手术后 25.3 个月时需要进行皮瓣不稳定的修正手术。位于足跟部(亚单位 5)的伤口最容易出现不稳定(Fisher 精确检验,p < 0.05)。Kaplan-Meier 分析确定的 5 年肢体保留率为 89%。
游离组织移植治疗足部和踝关节伤口与高保肢率相关。尽管可以使用多种皮瓣,但应用亚单位原理可以帮助外科医生设计解决亚单位特定功能和美学问题的皮瓣。