Department of Physics TAO, School of Optometry, University of Valladolid, Valladolid, Spain.
Eye Contact Lens. 2010 Jan;36(1):49-53. doi: 10.1097/ICL.0b013e3181c7bda6.
To determine the differences in symptoms associated with daily wear of silicone hydrogel (lotrafilcon B) contact lenses (CLs) after CL insertion and at the end of wear and their relationship with environmental factors and multipurpose solutions (Solo-care Aqua, CIBA Vision, Duluth, GA and Hidro Health, Disop, Spain).
Fifty-four patients were fitted with lotrafilcon B CLs. Two multipurpose solutions were randomly assigned and prescribed in a double-masked crossover study with three visits. After each solution was used, two questionnaires were conducted, including a survey produced by us and Contact Lens Dry Eye Questionnaire. Our questionnaire included 10 items addressing discomfort, blurry vision, lens-handling problems, dryness, redness, tearing, burning, itching, discharge, and dissatisfaction. Patients were assigned scores from 0 (without symptoms) to 10 (symptoms unbearable) at two different times (after CL insertion and at the end of wear) and in two environments (outdoors and adverse environments).
The average duration of CL wear was 8.32 +/- 2.27 hr/day and 5.85 +/- 1.30 days/week. All symptoms became worse (P < 0.05 Wilcoxon test, except lens handling) at the end of CL wear in all visits. The results were independent of the multipurpose solution used (P > 0.05 Friedman test), except for tearing, which showed statistical differences between visits (P = 0.03 Friedman test). Contact Lens Dry Eye Questionnaire showed increased dry eye symptoms at the end of wear (P < 0.05 Friedman test).
Daily wear symptoms associated with lotrafilcon B CL increase with the time of wear. This increase in symptoms is nonrelated with the multipurpose solutions compared in this study.
确定每日佩戴硅水凝胶(乐氧)隐形眼镜(CL)后与佩戴结束时与症状相关的差异,以及这些症状与环境因素和多功能隐形眼镜护理液(Solo-care Aqua,CIBA Vision, Duluth,GA 和 Hidro Health,Disop,Spain)的关系。
将 54 名患者适配乐氧 CL。在一项有 3 次就诊的双盲交叉研究中,患者随机分配并使用两种多功能隐形眼镜护理液。使用每种护理液后,患者填写我们的调查问卷和隐形眼镜干眼病问卷各一份。我们的问卷包括 10 个项目,涉及不适、视力模糊、镜片处理问题、干燥、发红、流泪、烧灼感、瘙痒、分泌物和不满。患者在两个不同时间(佩戴后和佩戴结束时)和两个环境(户外和不利环境)为每个项目分配 0(无症状)至 10(无法忍受的症状)的分数。
CL 的平均佩戴时间为 8.32 +/- 2.27 小时/天和 5.85 +/- 1.30 天/周。在所有就诊中,所有症状在佩戴结束时均恶化(P < 0.05 Wilcoxon 检验,除镜片处理外)。结果与使用的多功能隐形眼镜护理液无关(P > 0.05 Friedman 检验),除了流泪,其在就诊之间有统计学差异(P = 0.03 Friedman 检验)。隐形眼镜干眼病问卷显示佩戴结束时干眼症状增加(P < 0.05 Friedman 检验)。
与乐氧 CL 相关的每日佩戴症状随佩戴时间的增加而增加。与本研究中比较的多功能隐形眼镜护理液相比,这些症状的增加与佩戴时间有关。