婴儿期耐万古霉素粪肠球菌性脑膜炎：该病原体的特征及脑室注射达托霉素联合静脉注射替加环素的成功治疗。
Multidrug-resistant Enterococcus faecium meningitis in a toddler: characterization of the organism and successful treatment with intraventricular daptomycin and intravenous tigecycline.
机构信息
Department of Pediatrics, Seattle Children's Hospital, Seattle WA 98105, USA.
出版信息
Pediatr Infect Dis J. 2010 Apr;29(4):379-81. doi: 10.1097/INF.0b013e3181c806d8.
Abstract
A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive meningitis. She was successfully treated with intraventricular and intravenous daptomycin and intravenous tigecycline. The organism was characterized as a member of CC17, a notorious emerging nosocomial clone of Enterococcus faecium.
摘要
现报道一例幼儿肠球菌性脑膜炎。该菌对以往用于儿科革兰阳性菌脑膜炎的所有药物均高度耐药。经脑室和静脉万古霉素及静脉替加环素治疗后，该患儿痊愈。该菌被鉴定为 CC17 群的一员，这是一种臭名昭著的肠球菌粪肠球菌医院获得性新兴克隆。
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