患有无睾症或促性腺激素缺乏症男孩的长效睾酮治疗：对生长速率和成人身高的影响。
Depot testosterone in boys with anorchia or gonadotrophin deficiency: effect on growth rate and adult height.
作者信息
Moorthy B, Papadopolou M, Shaw D G, Grant D B
机构信息
Hospital for Children, London.
出版信息
Arch Dis Child. 1991 Feb;66(2):197-9. doi: 10.1136/adc.66.2.197.
Eleven teenage boys with bilateral anorchia and 12 with gonadotrophin deficiency were treated by injections of testosterone ester (enanthate) at an initial dose of 100 mg every six to eight weeks, rising to 250 mg every four weeks after three to four years. In the anorchic boys average adult height was 177.1 cm, compared with a mean mid-parental height of 174.4 cm, and mean predicted adult heights of 177.0 cm (Tanner-Whitehouse method) and 178.0 cm (Bayley-Pinneau method). In the patients with gonadotrophin deficiency, mean adult height was 176.9 cm, compared with a mean mid-parental height of 176.1 cm, and mean predicted adults heights of 174.0 cm (Tanner-Whitehouse method) and 177.3 cm (Bayley-Pinneau method). We conclude that this testosterone regimen allows achievement of full growth potential in such patients.
11名双侧无睾症青少年男性和12名促性腺激素缺乏症患者接受了睾酮酯（庚酸睾酮）注射治疗，初始剂量为每6至8周100毫克，3至4年后增至每4周250毫克。在无睾症男孩中，成人平均身高为177.1厘米，相比之下，父母平均身高为174.4厘米，使用坦纳 - 怀特豪斯方法预测的成人平均身高为177.0厘米，使用贝利 - 皮诺方法预测的为178.0厘米。在促性腺激素缺乏症患者中，成人平均身高为176.9厘米，相比之下，父母平均身高为176.1厘米，使用坦纳 - 怀特豪斯方法预测的成人平均身高为174.0厘米，使用贝利 - 皮诺方法预测的为177.3厘米。我们得出结论，这种睾酮治疗方案可使此类患者实现完全的生长潜能。
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