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加拿大一项综合减肥手术项目中腹腔镜可调节胃束带术和腹腔镜Roux-en-Y胃旁路术的五年疗效

Five-year outcomes of laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass in a comprehensive bariatric surgery program in Canada.

作者信息

Christou Nicolas, Efthimiou Evangelos

机构信息

Section of Bariatric Surgery, Division of General Surgery, McGill University Health Centre, Montréal, Que.

出版信息

Can J Surg. 2009 Dec;52(6):E249-58.

Abstract

BACKGROUND

Bariatric surgery remains the most effective modality to induce sustainable weight loss in the morbidly obese. Our aim was to compare outcomes between the laparoscopic Roux-en-Y gastric bypass (LRYGBP) and the laparoscopic adjustable gastric banding device (LAGBD) method with 5-year follow-up in a Canadian bariatric surgery centre.

METHODS

This is a retrospective outcomes analysis of 1035 laparoscopic bariatric procedures performed over 7 years. We extracted data from our prospectively collected bariatric surgery registry from Feb. 1, 2002, to Jun. 30, 2008. We evaluated patient demographics, weight loss, complications, mortality and need for revision surgery by procedure type.

RESULTS

We examined outcomes in 149 (14.4%) LAGBD and 886 (85.6%) LRYGBP procedures. The mean body mass index (BMI) was significantly higher in the LRYGBP group (50.9, standard deviation [SD] 8.9, v. 45.0, SD 6.7) whereas age and sex ratio were the same. There were 3 deaths (0.3%) in the LRYGBP group and no deaths in the LAGBD group. Sixteen patients (10.8%) in the LAGBD group needed conversion to LRYGBP because of poor weight loss, band intolerance, band erosion or slippage, and 6 patients (0.7%) in the LRYGBP group required revision because of inability to achieve the desired weight loss. The percent excess-weight loss was 41, 49, 59, 60 and 61 at 1, 2, 3, 4 and 5 years postsurgery for the LAGBD patients who kept their band, and 70, 79, 79, 79 and 75 for the LRYGBP patients.

CONCLUSION

Laparoscopic weight loss surgery can be performed safely with acceptable mortality. Our study suggests superior weight loss and low revision requirement for the LRYGBP, making this a more durable procedure in a publicly funded health care system.

摘要

背景

减肥手术仍然是使病态肥胖者实现可持续体重减轻的最有效方式。我们的目的是在加拿大一家减肥手术中心对腹腔镜Roux-en-Y胃旁路术(LRYGBP)和腹腔镜可调节胃束带装置(LAGBD)方法进行5年随访后的结果进行比较。

方法

这是一项对7年内进行的1035例腹腔镜减肥手术的回顾性结果分析。我们从2002年2月1日至2008年6月30日前瞻性收集的减肥手术登记处提取数据。我们按手术类型评估患者的人口统计学特征、体重减轻情况、并发症、死亡率以及翻修手术需求。

结果

我们检查了149例(14.4%)LAGBD手术和886例(85.6%)LRYGBP手术的结果。LRYGBP组的平均体重指数(BMI)显著更高(50.9,标准差[SD]8.9,对比45.0,SD 6.7),而年龄和性别比例相同。LRYGBP组有3例死亡(0.3%),LAGBD组无死亡病例。LAGBD组有16例患者(10.8%)因体重减轻不佳、束带不耐受、束带侵蚀或滑脱而需要转为LRYGBP手术,LRYGBP组有6例患者(0.7%)因未能实现预期体重减轻而需要翻修。保留束带的LAGBD患者在术后1、2、3、4和五年时的超重体重减轻百分比分别为41%、49%、59%、60%和61%,LRYGBP患者分别为70%、79%、79%、79%和75%。

结论

腹腔镜减肥手术可以安全进行,死亡率可接受。我们的研究表明,LRYGBP的体重减轻效果更佳且翻修需求较低,使其在公共资助的医疗保健系统中成为一种更持久的手术方式。

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