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韩国腹腔镜 Roux-en-Y 胃旁路术和可调胃束带术的初步评估:单中心研究。

Initial evaluation of laparoscopic Roux-en-Y gastric bypass and adjustable gastric banding in Korea: a single institution study.

机构信息

Division of Laparoscopic & Bariatric Surgery, Department of Surgery, St. Mary's Hospital, College of Medicine, The Catholic University of Korea, #62 Yeouido-dong, Yeongdeungpo-gu, Seoul, 150-713, South Korea.

出版信息

Obes Surg. 2010 Aug;20(8):1096-101. doi: 10.1007/s11695-008-9528-5. Epub 2008 Apr 29.

Abstract

BACKGROUND

Obesity becomes a global epidemic disease, and bariatric surgery is increasing in Korea as well as in western countries. The first laparoscopic Roux-en-Y gastric bypass (LRYGBP) was performed in 2003, and the Lap Band was approved for use in Korea in 2004. There are no data regarding gastric bypass and adjustable gastric banding regarding weight loss as well as changing of pre-existing comorbidities up to date.

METHODS

St. Mary's Hospital Center, main leader of bariatric surgery in Korea, performed 76 weight loss operations [LRYGBP = 25, laparoscopic adjustable gastric banding (LAGB) = 51] for morbid obesity. We retrospectively reviewed a series of bariatric cases and examined changes of weight loss, postoperative complications, and pre-existing comorbidities between two procedures.

RESULTS

There were no significant differences in age, BMI, sex distribution, pre-existing comorbidities in two procedures. Patients undergoing LRYGBP had longer operative times, more blood loss, and longer hospital stays. There is significant difference regarding postoperative complication (p < 0.05) but neither for mortality nor pulmonary embolism with both procedures. Percentage of excess weight loss (%EWL) of LRYGBP at 12, 24, and 36 months were 76.9%, 79.7%, and 85.8%, and %EWL of LAGB were 46.8%, 55.1%, 63.3%, respectively. The patients in the LRYGBP who has dyslipidemia, sleep apnea, degenerative joint disease, and diabetes mellitus were more likely to improve than the patients after LAGB at early postoperative period.

CONCLUSIONS

The results of our initial study indicate that LRYGBP and LAGB are technically feasible and safe. It is a low rate of major postoperative complications without mortality. LRYGBP and LAGB are quite satisfactory and promising bariatric procedures with significant weight loss and improvement of obesity-related metabolic comorbidities in Korean.

摘要

背景

肥胖已成为全球性流行病,在西方国家和韩国,减重手术的数量都在不断增加。首例腹腔镜 Roux-en-Y 胃旁路术(LRYGBP)于 2003 年开展,胃带于 2004 年在韩国获得批准使用。目前尚无关于胃旁路术和可调胃束带术的减重效果以及对现有并存疾病的改变的数据。

方法

韩国主要的减重手术中心圣玛丽医院对 76 例病态肥胖患者进行了减重手术[LRYGBP=25,腹腔镜可调胃束带术(LAGB)=51]。我们回顾性地分析了一系列减重手术病例,并检查了两种手术在减重、术后并发症和并存疾病方面的变化。

结果

两种手术在年龄、BMI、性别分布、并存疾病方面无显著差异。LRYGBP 组的手术时间较长、失血量较多、住院时间较长。两种手术的术后并发症(p<0.05)有显著差异,但死亡率和肺栓塞均无差异。LRYGBP 组术后 12、24 和 36 个月的多余体重减轻百分比(%EWL)分别为 76.9%、79.7%和 85.8%,LAGB 组分别为 46.8%、55.1%和 63.3%。LRYGBP 组中患有血脂异常、睡眠呼吸暂停、退行性关节病和糖尿病的患者在术后早期比 LAGB 组患者更有可能得到改善。

结论

我们的初步研究结果表明,LRYGBP 和 LAGB 技术上是可行和安全的。两种手术的主要术后并发症发生率低,且无死亡率。LRYGBP 和 LAGB 是两种令人满意且有前途的减重手术,在韩国,它们能显著减轻体重并改善肥胖相关的代谢合并症。

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