Department of Food and Nutritional Sciences, University College of Cork, Cork, Ireland.
Food Nutr Res. 2009 Nov 12;53:2038. doi: 10.3402/fnr.v53i0.2038.
Recent European Union regulation requires setting of maximum amount of micronutrients in dietary supplements or foods taking into account the tolerable upper intake level (ULs) established by scientific risk assessment and population reference intakes.
To collect and evaluate recently available data on intakes of selected vitamins and minerals from conventional foods, food supplements and fortified foods in adults and children. Intake of calcium, copper, iodine, iron, magnesium, phosphorus, selenium, zinc, folic acid, niacin and total vitamin A/retinol, B(6), D and E was derived from nationally representative surveys in Denmark, Germany, Finland, Ireland, Italy, the Netherlands, Poland, Spain and the United Kingdom. Intake of high consumers, defined as the 95th percentile of each nutrient, was compared to the UL.
For most nutrients, adults and children generally consume considerably less than the UL with exceptions being retinol, zinc, iodine, copper and magnesium. The major contributor to intakes for all nutrients and in all countries is from foods in the base diet. The patterns of food supplements and voluntary fortification vary widely among countries with food supplements being responsible for the largest differences in total intakes. In the present study, for those countries with data on fortified foods, fortified foods do not significantly contribute to higher intakes for any nutrient. Total nutrient intake expressed as percentage of the UL is generally higher in children than in adults.
The risk of excessive intakes is relatively low for the majority of nutrients with a few exceptions. Children are the most vulnerable group as they are more likely to exhibit high intakes relative to the UL. There is a need to develop improved methods for estimating intakes of micronutrients from fortified foods and food supplements in future dietary surveys.
最近欧盟的规定要求根据科学风险评估和人群参考摄入量确定的可耐受最高摄入量 (ULs),来设定膳食补充剂或食品中微量营养素的最大含量。
收集和评估最近成人和儿童从常规食品、食品补充剂和强化食品中摄取选定维生素和矿物质的数据。钙、铜、碘、铁、镁、磷、硒、锌、叶酸、烟酸和总维生素 A/视黄醇、B(6)、D 和 E 的摄入量来自丹麦、德国、芬兰、爱尔兰、意大利、荷兰、波兰、西班牙和英国的全国代表性调查。摄入量高的人群(定义为每种营养素的第 95 个百分位)与 UL 进行了比较。
对于大多数营养素,成人和儿童的摄入量通常远低于 UL,除了视黄醇、锌、碘、铜和镁。所有营养素和所有国家的摄入量主要来自基础饮食中的食物。食品补充剂和自愿强化的模式在各国之间差异很大,食品补充剂对总摄入量的差异影响最大。在本研究中,对于有强化食品数据的国家,强化食品对任何营养素的摄入量增加都没有显著贡献。以 UL 的百分比表示的营养素总摄入量在儿童中通常高于成人。
对于大多数营养素,过量摄入的风险相对较低,但也有一些例外。儿童是最脆弱的群体,因为他们比 UL 更容易出现高摄入量。需要开发改进的方法,以便在未来的饮食调查中估算强化食品和食品补充剂中微量营养素的摄入量。