Landmann Ron G, Weiser Martin R
Department of Surgery, Division of Colorectal Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Clin Colon Rectal Surg. 2005 Aug;18(3):182-9. doi: 10.1055/s-2005-916279.
Locally advanced and locally recurrent colon cancers pose a surgical challenge with tumors extending into surrounding structures and organs. Anticipation of the need for an extended surgical resection, often with multivisceral en bloc organ removal, is critical for surgical planning. For both primary and recurrent tumors, postsurgical long-term survival is achievable but only after complete resection. The role of neoadjuvant and adjuvant therapy continues to be redefined in this era of biologic chemotherapeutics, and multimodality therapy holds promise in aiding resection and improving postsalvage survival.
局部进展期和局部复发性结肠癌对手术构成挑战，肿瘤会侵犯周围结构和器官。预计通常需要进行多脏器整块切除的扩大手术切除，这对手术规划至关重要。对于原发性和复发性肿瘤，术后长期生存是可以实现的，但前提是必须完全切除。在生物化疗时代，新辅助治疗和辅助治疗的作用仍在不断重新定义，多模式治疗有望辅助切除并提高挽救术后的生存率。
