Singh Anurag, Kaur Mandeep, Baig Mirza K, Swaminathan Christie, Subramanian Atreya, Sajid Muhammad S
Department of Gastrointestinal Surgery, Royal Sussex County Hospital, Brighton, UK.
Department of Colorectal Surgery, Worthing Hospital, Worthing, UK.
Transl Gastroenterol Hepatol. 2024 Apr 17;9:21. doi: 10.21037/tgh-23-73. eCollection 2024.
Robotic colorectal resections (RCR) have been gaining popularity recently due to several advantages in addition to oncological safety. The objective of this review is to evaluate the cost comparison of RCR versus laparoscopic colorectal resections (LCR).
All types of comparative studies reporting the cost of RCR versus LCR were retrieved from the search of standard medical electronic databases and analysis was conducted by using the principles of meta-analysis on the statistical software RevMan version 5.
The search of medical databases yielded 13 studies (one randomised trial and 12 comparative studies) on 16,082 patients undergoing oncological and non-oncological colorectal resections. Eleven studies reported total cost whereas seven studies reported only operative cost. In the random effects model analysis, LCR was associated with the reduced total cost [standardised mean difference -62.34, 95% confidence interval (CI): -75.14 to -49.54, Z=9.55, P<0.001] as well as reduced operative cost (standardised mean difference -4.60, 95% CI: -5.90 to -3.31, Z=6.96, P<0.001) compared to RCR. However, there was significant heterogeneity [Tau=346.74, Chi=29,559.11, df =11 (P<0.001; I=100%); Tau=2.73, Chi=832.21, df =6 (P<0.001; I=99%)] among included studies.
The LCR seems to be more economical as compared to the RCR in terms of operative cost as well as total cost (operative plus in-patient stay). However, due to statistically significant heterogeneity among included studies and paucity of the randomised trials, these findings should be taken cautiously.
除肿瘤学安全性外,机器人结直肠切除术(RCR)因其多项优势,近年来越来越受欢迎。本综述的目的是评估RCR与腹腔镜结直肠切除术(LCR)的成本比较。
通过检索标准医学电子数据库,获取所有报告RCR与LCR成本的比较研究类型,并使用RevMan 5版统计软件,依据荟萃分析原则进行分析。
医学数据库检索共纳入13项研究(1项随机对照试验和12项比较研究),涉及16082例行肿瘤性和非肿瘤性结直肠切除术的患者。11项研究报告了总成本,7项研究仅报告了手术成本。随机效应模型分析显示,与RCR相比,LCR的总成本降低[标准化均数差-62.34,95%置信区间(CI):-75.14至-49.54,Z=9.55,P<0.001],手术成本也降低(标准化均数差-4.60,95%CI:-5.90至-3.31,Z=6.96,P<0.001)。然而,纳入研究间存在显著异质性[Tau=346.74,Chi=29559.11,自由度=11(P<0.001;I=100%);Tau=2.73,Chi=832.21,自由度=6(P<未找到相关内容001;I=99%)]。
就手术成本以及总成本(手术加住院时间)而言,LCR似乎比RCR更经济。然而,由于纳入研究间存在统计学显著异质性且随机对照试验较少,这些结果应谨慎看待。