Papaconstantinou Harry T, Thomas J Scott
Department of Surgery, Division of Surgical Oncology, Texas A&M University System Health Science Center, Scott and White Hospital, Temple, TX 76508, USA.
Clin Colon Rectal Surg. 2007 Feb;20(1):18-27. doi: 10.1055/s-2007-970196.
Bacterial colitis results in an inflammatory-type diarrhea that is characterized by bloody, purulent, and mucoid stool. These diseases have been designated as bacterial hemorrhagic enterocolitis. Associated symptoms include fever, tenesmus, and severe abdominal pain. The pathologic changes range from superficial exudative enterocolitis to a transmural enterocolitis with ulceration. Common pathologic bacteria causing bacterial colitis include Campylobacter, Salmonella, Shigella, Escherichia, and Yersinia species. The primary source of transmission is fecal-oral spread and ingestion of contaminated food and water. Although detailed history and identification of specific risk factors assist in the diagnosis, definitive diagnosis requires bacterial identification. Therefore, the physician must be familiar with the disease pathophysiology, epidemiology, and specific diagnostic modalities for clinical diagnosis and management. Specific tests are used to detect enteric pathogens and include stool and rectal swab culture, histology, and identification of specific bacterial toxins. Although many of these bacterial colitis infections are self-limiting, antibiotics should be used for high-risk patients and patients with complicated disease.
细菌性结肠炎会导致炎症性腹泻,其特征为粪便带血、有脓性和黏液。这些疾病被称为细菌性出血性小肠结肠炎。相关症状包括发热、里急后重和严重腹痛。病理变化范围从浅表性渗出性小肠结肠炎到伴有溃疡的全壁性小肠结肠炎。引起细菌性结肠炎的常见病原菌包括弯曲杆菌、沙门菌、志贺菌、大肠埃希菌和耶尔森菌属。主要传播途径是粪口传播以及摄入受污染的食物和水。尽管详细的病史和特定危险因素的识别有助于诊断,但明确诊断需要进行细菌鉴定。因此,医生必须熟悉该疾病的病理生理学、流行病学以及用于临床诊断和管理的特定诊断方法。特定检测用于检测肠道病原体,包括粪便和直肠拭子培养、组织学检查以及特定细菌毒素的鉴定。尽管许多此类细菌性结肠炎感染是自限性的,但对于高危患者和患有复杂疾病的患者应使用抗生素。