Gow-Lee Benjamin, Bennett Phillip, Schmitt Jessicia, Kashani Amir
Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Case Rep Gastrointest Med. 2025 Jul 26;2025:1627615. doi: 10.1155/crgm/1627615. eCollection 2025.
Diagnosing inflammatory bowel disease (IBD) can be challenging in the presence of mimicking conditions, such as infectious colitis. An accurate diagnosis is important to avoid unnecessary treatment. Nontyphoidal species are an important cause of infectious colitis that at times can mimic IBD. serotype Saintpaul has caused numerous fatal foodborne gastroenteritis outbreaks worldwide. It has also been known to cause other infections, such as bacteremia, splenic abscesses, and meningitis, but has only rarely been known to cause colitis. Worryingly, antibiotic resistance rates of S. Saintpaul are rising. This case report presents a woman with S. Saintpaul colitis mimicking Crohn's disease. Despite an initial plan to start biologic therapy, long-term follow-up while off immunosuppressant therapy confirmed S. Saintpaul as the underlying cause of colitis, sparing our patient long-term immunosuppression. This case highlights the importance of ruling out infectious colitis before beginning long-term immunosuppressive therapy and the challenges of mimicking conditions as well as the novelty of the Saintpaul serotype causing colitis.
在存在诸如感染性结肠炎等类似病症的情况下，诊断炎症性肠病（IBD）可能具有挑战性。准确的诊断对于避免不必要的治疗很重要。非伤寒菌种是感染性结肠炎的一个重要病因，有时可模仿IBD。圣保罗血清型已在全球范围内引发了众多致命的食源性胃肠炎疫情。它也已知会引起其他感染，如菌血症、脾脓肿和脑膜炎，但很少已知会引起结肠炎。令人担忧的是，圣保罗沙门氏菌的抗生素耐药率正在上升。本病例报告介绍了一名患有模仿克罗恩病的圣保罗沙门氏菌结肠炎的女性。尽管最初计划开始生物治疗，但在停用免疫抑制治疗后的长期随访证实圣保罗沙门氏菌是结肠炎的根本原因，使我们的患者免于长期免疫抑制。本病例强调了在开始长期免疫抑制治疗之前排除感染性结肠炎的重要性、类似病症的挑战以及引起结肠炎的圣保罗血清型的新颖性。
