Shiba Hiroaki, Misawa Takeyuki, Wakiyama Shigeki, Iida Tomonori, Ishida Yuichi, Yanaga Katsuhiko
Department of Surgery, Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
J Gastrointest Cancer. 2010 Jun;41(2):138-40. doi: 10.1007/s12029-009-9099-2.
A 30-year-old woman was admitted to our hospital for treatment of an ampullary tumor. Upper gastrointestinal endoscopy revealed a pedunculated tumor in the ampulla of Vater with a diameter of 50 mm, which was biopsied and diagnosed as tubulovillous adenoma with moderate atypia. Endoscopic ultrasonography demonstrated a hypoechoic tumor limited to the mucosa and without evidence of lymph node metastasis. Since endoscopic resection was not indicated because of the large size and pedunculated morphology with a long stalk, the patient underwent ampullectomy and papilloplasty. Histological examination revealed well-differentiated tubular adenocarcinoma in tubular adenoma with severe atypia limited to the mucosa. The patient remains well with no evidence of recurrence 10 months after resection.
Ampullectomy is an established method for ampullary tumor, but such a tumor with a long stalk is rare.
一名30岁女性因壶腹肿瘤入院治疗。上消化道内镜检查发现 Vater 壶腹有一个直径50 mm的带蒂肿瘤,对其进行活检,诊断为中度异型增生的管状绒毛状腺瘤。内镜超声显示低回声肿瘤局限于黏膜,无淋巴结转移迹象。由于肿瘤体积较大且带蒂形态有长蒂,不适合内镜切除,患者接受了壶腹切除术和乳头成形术。组织学检查显示管状腺瘤中存在高分化管状腺癌,重度异型增生局限于黏膜。切除术后10个月,患者情况良好,无复发迹象。
壶腹切除术是治疗壶腹肿瘤的既定方法,但这种带长蒂肿瘤较为罕见。