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神经生理学引导下的阴部神经调节:难治性慢性盆腔 - 会阴疼痛的一种潜在治疗选择。

Pudendal nerve neuromodulation with neurophysiology guidance: a potential treatment option for refractory chronic pelvi-perineal pain.

作者信息

Carmel Maude, Lebel Michel, Tu Le Mai

机构信息

Department of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada.

出版信息

Int Urogynecol J. 2010 May;21(5):613-6. doi: 10.1007/s00192-009-1054-z. Epub 2009 Dec 12.

DOI:10.1007/s00192-009-1054-z
PMID:20012596
Abstract

Refractory chronic pelvi-perineal pain (RCPPP) is a challenging entity that has devastating consequences for patient's quality of life. Many etiologies have been proposed including pudendal neuralgia. Multiple treatment options are used but the reported results are sub-optimal and temporary. In this article, we present the technique of pudendal nerve neuromodulation with neurophysiology guidance as a treatment option for RCPPP. This technique is a two-step procedure that includes electrode implantation under neurophysiology guidance followed by the implantation of a permanent generator after a successful trial period. We report the cases of three women who underwent this procedure as a last-resort treatment option. After 2 years of follow-up, their symptoms are still significantly improved. No major complication occurred.

摘要

难治性慢性盆腔 - 会阴疼痛(RCPPP)是一种具有挑战性的病症,对患者的生活质量有着毁灭性的影响。已经提出了许多病因,包括阴部神经痛。虽然使用了多种治疗方法,但报告的结果并不理想且只是暂时的。在本文中,我们介绍了在神经生理学引导下进行阴部神经调节的技术,作为RCPPP的一种治疗选择。该技术是一个两步程序,包括在神经生理学引导下植入电极,然后在成功的试验期后植入永久发生器。我们报告了三名女性患者的病例,她们将此程序作为最后的治疗选择。经过2年的随访,她们的症状仍有显著改善。未发生重大并发症。

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本文引用的文献

1
Pudendal neuralgia. Fact or fiction?阴部神经痛。事实还是虚构?
Obstet Gynecol Surv. 2009 Mar;64(3):190-9. doi: 10.1097/ogx.0b013e318193324e.
2
Diagnostic criteria for pudendal neuralgia by pudendal nerve entrapment (Nantes criteria).阴部神经卡压所致阴部神经痛的诊断标准(南特标准)。
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Sacral versus pudendal nerve stimulation for voiding dysfunction: a prospective, single-blinded, randomized, crossover trial.骶神经刺激与阴部神经刺激治疗排尿功能障碍:一项前瞻性、单盲、随机、交叉试验。
经皮胫神经刺激对埃及多产阴道松弛女性的影响:一项随机对照试验
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Pudendal Neuralgia: A Review of the Current Literature.阴部神经痛:当前文献综述
Curr Pain Headache Rep. 2025 Jan 28;29(1):38. doi: 10.1007/s11916-024-01354-z.
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Current role of neuromodulation in bladder pain syndrome/interstitial cystitis.神经调节在膀胱疼痛综合征/间质性膀胱炎中的当前作用。
Ther Adv Urol. 2022 Nov 21;14:17562872221135941. doi: 10.1177/17562872221135941. eCollection 2022 Jan-Dec.
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Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review.用于慢性盆腔疼痛管理的神经调节:一项综述
Pain Ther. 2022 Dec;11(4):1137-1177. doi: 10.1007/s40122-022-00430-9. Epub 2022 Sep 15.
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Neuromodulation for Pelvic and Urogenital Pain.用于盆腔和泌尿生殖系统疼痛的神经调节
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[Neuromodulation - new techniques].[神经调节——新技术]
Urologe A. 2015 Mar;54(3):373-7. doi: 10.1007/s00120-014-3686-y.
9
Percutaneous CT-guided cryoablation for the treatment of refractory pudendal neuralgia.经皮CT引导下冷冻消融术治疗难治性阴部神经痛
Skeletal Radiol. 2015 May;44(5):709-14. doi: 10.1007/s00256-014-2075-3. Epub 2014 Dec 17.
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Neurourol Urodyn. 2005;24(7):643-7. doi: 10.1002/nau.20174.
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A new minimally invasive procedure for pudendal nerve stimulation to treat neurogenic bladder: description of the method and preliminary data.一种用于治疗神经源性膀胱的新型阴部神经刺激微创方法:方法描述及初步数据
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Chronic perineal pain caused by pudendal nerve entrapment: anatomy and CT-guided perineural injection technique.阴部神经卡压所致慢性会阴部疼痛:解剖学与CT引导下神经周围注射技术
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