Endocrine Surgery Research Center, Department of Surgical Sciences, University of Insubria (Varese-Como), Via Guicciardini 21100, Varese, Italy.
Langenbecks Arch Surg. 2010 Apr;395(4):327-31. doi: 10.1007/s00423-009-0581-x. Epub 2009 Dec 15.
There is currently a lack of consensus to support the proper timing for postoperative laryngoscopy that is reliable to diagnose recurrent laryngeal nerve palsy (RLNP) after thyroid surgery. The purpose of this study was to investigate the impact of different time intervals of fiber-optic nasolaryngoscopy (FNL) on the diagnosis of RLNP.
FNL was performed postoperatively at day 0 (T1), at second day post-op (T2), and +2 weeks (T3). For patients with RLNP, repeated examinations were performed at +2 (T4), +6 (T5), and +12 months (T6).
Four hundred thirty-four patients appear for postoperative FNL, providing 825 nerves at risk. Permanent RLNP occurred in 0.7%, temporary RLNP in 6.7%. RLNP rate was 6.4% at T1, 6.7% at T2, 4.8% at T3, 2.5% at T4, 0.8% at T5, and 0.7% at T6. Full recovery of vocal cord function was confirmed after rehabilitation in 87.5% of cases at T5 and 89% in T6. T2 was significantly superior to T3 in terms of diagnosis of RLNP (P < 0.05). Of patients at T2, 10.7% did not see any reason to FNL because of their normal voice register.
FNL is essential for the detection of vocal cord paralysis after thyroidectomy. We report different time evaluation criteria of vocal cord motility with great and significant variability of results. Second day post-op inspection of the larynx (T2) is suggested. Symptomatic voice assessment is insufficient.
目前缺乏可靠的共识来支持甲状腺手术后诊断喉返神经麻痹(RLNP)的术后喉镜检查的适当时机。本研究旨在探讨不同时间间隔行纤维鼻咽喉镜(FNL)检查对 RLNP 诊断的影响。
术后第 0 天(T1)、术后第 2 天(T2)和+2 周(T3)进行 FNL。对于 RLNP 患者,在+2 天(T4)、+6 天(T5)和+12 个月(T6)时进行重复检查。
434 例患者接受了术后 FNL 检查,共检查了 825 条有风险的神经。永久性 RLNP 发生率为 0.7%,暂时性 RLNP 发生率为 6.7%。T1 时 RLNP 发生率为 6.4%,T2 时为 6.7%,T3 时为 4.8%,T4 时为 2.5%,T5 时为 0.8%,T6 时为 0.7%。在 T5 时,87.5%的患者经康复后证实声带功能完全恢复,在 T6 时为 89%。T2 在诊断 RLNP 方面明显优于 T3(P<0.05)。在 T2 的患者中,10.7%因声音正常而无需进行 FNL。
FNL 对于检测甲状腺切除术后声带麻痹至关重要。我们报告了声带运动不同时间评估标准,结果存在很大差异。建议术后第 2 天(T2)检查喉部。症状性语音评估是不够的。