Brierley J D, Paterson I C, Lallemand R C, Rostom A Y
Regional Centre for Radiotherapy and Oncology, St Luke's Hospital, Guildford, Surrey.
Clin Oncol (R Coll Radiol). 1991 Jan;3(1):6-9. doi: 10.1016/s0936-6555(05)81031-3.
The correlation between late radiation reaction and brassiere size (bust and cup size) in 133 patients with T1 and T2 breast cancer treated by excision and radiotherapy was examined. The radiotherapy schedule used was 4875 cGy in 15 x 3.25 Gy fractions over 39 days treating five times per fortnight. Patients were followed up to a minimum of 2 years (median 4.2 years). The incidence of unacceptable late radiation reaction rose significantly with bust size (P less than 0.001) and cup size (P less than 0.02). It is intended to treat ladies with large breasts with a reduced fraction size or on a daily basis.
对133例接受切除和放疗的T1和T2期乳腺癌患者，研究了迟发性放射反应与胸罩尺寸（胸围和罩杯尺寸）之间的相关性。所采用的放疗方案是在39天内给予4875 cGy，分15次，每次3.25 Gy，每两周治疗5次。对患者进行了至少2年的随访（中位随访时间为4.2年）。不可接受的迟发性放射反应的发生率随胸围尺寸（P<0.001）和罩杯尺寸（P<0.02）显著升高。计划对乳房较大的女性采用较小的分次剂量或每日进行治疗。
