International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi 75270, Pakistan.
Nat Prod Res. 2010;24(1):1-6. doi: 10.1080/14786410701614507.
Transformation of lynestrenol (19-nor-17alpha-pregn-4-en-20-yn-17beta-ol) (1) was carried out by incubation with Cunninghamella elegans to obtain 19-nor-17alpha-pregn-4-en-20-yn-3-one-10beta,17beta-diol (2), 19-nor-17alpha-pregn-4-en-20-yn-3-one-6beta,17beta-diol (3), and 19-nor-17alpha-pregn-4-en-20-yn-3beta,6beta,17beta-triol (4). Metabolite 4 was identified as a new compound. These metabolites were structurally characterised on the basis of spectroscopic techniques.
林司特龙（19-去甲-17α-孕甾-4-烯-20-炔-17β-醇）（1）经培养中华被毛孢转化为 19-去甲-17α-孕甾-4-烯-20-炔-3-酮-10β，17β-二醇（2）、19-去甲-17α-孕甾-4-烯-20-炔-3-酮-6β，17β-二醇（3）和 19-去甲-17α-孕甾-4-烯-20-炔-3β，6β，17β-三醇（4）。代谢物 4 被鉴定为一种新化合物。这些代谢物基于光谱技术进行了结构表征。
