某些欧洲国家的春黄菊（L.）Rauschert 精油的成分和组成。

Content and composition of the essential oil of Chamomilla recutita (L.) Rauschert from some European countries.

机构信息

Institute of Chemistry, Tallinn University of Technology, Tallinn, Estonia.

出版信息

Nat Prod Res. 2010;24(1):48-55. doi: 10.1080/14786410802560690.

PMID:20013472

Abstract

Variations in the essential oil composition of Chamomilla recutita (L.) Rauschert from different European countries were determined. A total of 39 components were identified, representing over 92% of the total oil yield. The principal biologically active compounds in chamomile oils were bisabolol oxide A (3.1-56.0%), alpha-bisabolol (0.1-44.2%), bisabolol oxide B (3.9-27.2%), cis-enyne-bicycloether (8.8-26.1%), bisabolon oxide A (0.5-24.8%), chamazulene (0.7-15.3%), spathulenol (1.7-4.8%) and (E)-beta-farnesene (2.3-6.6%). In 8 chamomile samples from 13, bisabolol oxide A (27.5-56.0%) was predominant (among them in three Estonian samples). alpha-Bisabolol (23.9-44.2%) was predominant in the samples from Moldova, Russia and the Czech Republic. The sample from Armenia was rich in bisabolol oxide B (27.2%) and chamazulene (15.3%). The oils were obtained in yields of 0.7-6.7 mL kg(-1) and the minimum limit of 4 mL kg(-1) stated by the European Pharmacopoeia was exceeded only in 13 samples from 13 analysed drugs.

摘要

不同欧洲国家的春黄菊（Chamomilla recutita（L.）Rauschert）的精油成分存在差异。共鉴定出 39 种成分，占总油产量的 92%以上。在甘菊油中主要的生物活性化合物是：倍半萜氧化物 A（3.1-56.0%）、α- 倍半萜醇（0.1-44.2%）、倍半萜氧化物 B（3.9-27.2%）、顺式-炔-双环醚（8.8-26.1%）、α- 倍半萜醇氧化物 A（0.5-24.8%）、母菊薁（0.7-15.3%）、斯巴醇（1.7-4.8%）和（E）-β-法呢烯（2.3-6.6%）。在 13 个国家的 8 个春黄菊样本中，倍半萜氧化物 A（27.5-56.0%）占主导地位（其中 3 个爱沙尼亚样本中含量最高）。摩尔多瓦、俄罗斯和捷克共和国的样本中 α- 倍半萜醇（23.9-44.2%）占主导地位。亚美尼亚样本富含倍半萜氧化物 B（27.2%）和母菊薁（15.3%）。这些油的产量为 0.7-6.7 mL/kg，仅在 13 个分析样本中有 13 个超过了欧洲药典规定的最低限量 4 mL/kg。