Kosińska Magdalena, Kraus-Filarska Maria
Katedra i Klinika Chorób Wewnetrznych, Geriatrii i Alergologii we Wrocławiu.
Pneumonol Alergol Pol. 2009;77(6):541-8.
Atypical microorganism infections, including Chlamydophila pneumoniae, play an important role in asthma course. A significant influence of chlamydial infection on severity of asthma exacerbations and increase in chronic asthma symptoms has been shown. The group of medication with high antibacterial activity against atypical microorganisms are macrolides, which also have anti-inflammatory and immunomodulatory effects. Macrolide treatment in patients with asthma can be connected with additional therapeutic benefits. Mechanism of action of these antibiotics is not ultimately clarified and further studies are required.
非典型微生物感染，包括肺炎衣原体，在哮喘病程中起重要作用。衣原体感染对哮喘加重的严重程度和慢性哮喘症状的增加有显著影响。对非典型微生物具有高抗菌活性的药物类别是大环内酯类，其也具有抗炎和免疫调节作用。哮喘患者的大环内酯类治疗可能带来额外的治疗益处。这些抗生素的作用机制尚未最终阐明，需要进一步研究。
