Tufts University School of Medicine, Boston, MA 02111, USA.
Pharmacoepidemiol Drug Saf. 2010 Feb;19(2):115-23. doi: 10.1002/pds.1878.
Electronic prescription monitoring programs (PMPs) have been developed in many states as a public health surveillance tool. We analyze herein 11 years of Massachusetts PMP data to evaluate trends in opioid prescribing, dispensing, and usage.
Prescription records from the Massachusetts PMP for Schedule II opioids from fiscal year 1996 to 2006 were analyzed. 'Questionable activity' (potential 'doctor shopping') estimates were based on individual use of multiple prescribers and pharmacies, and early refills.
The number of prescriptions, doses prescribed, and individuals receiving Schedule II prescription opioids steadily increased from 1996 to 2006. Most individuals (87.5%) used 1-2 prescribers, 1-2 pharmacies, and had no early refills (2006). The greater the number of prescribers used, the greater the number of pharmacies used. When defined as the use of >or=4 prescribers and >or=4 pharmacies, questionable activity accounted for 2748 individuals, 47 953 prescriptions, and 2 966 056 doses (2006). The Schedule II opioid most highly associated with questionable activity was short-acting oxycodone.
PMPs can become a useful public health surveillance tool to monitor the medical and non-medical use of prescription opioids and to inform public health and safety policy.
电子处方监测计划（PMP）已在许多州开发，作为公共卫生监测工具。我们在此分析马萨诸塞州 PMP 11 年的数据，以评估阿片类药物处方、配药和使用的趋势。
分析了 1996 年至 2006 年马萨诸塞州 PMP 中治疗计划 II 类阿片类药物的处方记录。可疑活动（潜在的“医生购物”）估计基于个人使用多个处方者和药店，以及早期的续药。
1996 年至 2006 年，处方数量、开处剂量和接受 II 类处方阿片类药物的人数稳步增加。大多数人（87.5%）使用 1-2 名处方者、1-2 家药店，且没有早期续药（2006 年）。使用的处方者越多，使用的药店就越多。当定义为使用> = 4 名处方者和> = 4 家药店时，可疑活动涉及 2748 人、47953 张处方和 2966056 剂（2006 年）。与可疑活动相关性最高的 II 类阿片类药物是短效羟考酮。
PMP 可以成为一种有用的公共卫生监测工具，用于监测处方阿片类药物的医疗和非医疗用途，并为公共卫生和安全政策提供信息。
