Handa Uma, Singhal Niti, Punia Rajpal Singh, Garg Sudhir, Mohan Harsh
Department of Pathology, Government Medical College, Chandigarh, India.
Acta Cytol. 2009 Nov-Dec;53(6):704-6. doi: 10.1159/000325415.
Extraskeletal myxoid chondrosarcoma (EMC) is an uncommon tumor. On fine needle aspiration (FNA) it has to be distinguished from other benign and malignant soft tissue lesions.
FNA was done on an 85-year-old man with painful swelling of the forearm. Smears showed fragments comprised of polygonal cells with eccentric nuclei and peripheral fine cytoplasmic vacuoles embedded in a dense, metachromatic matrix. Cell block showed similar cells in a chondromyxoid stroma. The cells were positive for S100 and negative for cytokeratin.
FNA is a useful tool in the diagnosis of EMC in conjunction with radiology. A preoperative diagnosis can be made due to its distinct cytologic and immunohistochemical features, obviating the need for a biopsy.
骨外黏液样软骨肉瘤（EMC）是一种罕见肿瘤。在细针穿刺抽吸活检（FNA）中，必须将其与其他良恶性软组织病变区分开来。
对一名85岁前臂疼痛肿胀男性进行了FNA。涂片显示碎片由多边形细胞组成，细胞核偏位，周围有细小的胞质空泡，嵌入致密的异染性基质中。细胞块显示在软骨黏液样基质中有类似细胞。细胞S100阳性，细胞角蛋白阴性。
FNA结合放射学检查是诊断EMC的有用工具。因其独特的细胞学和免疫组化特征可进行术前诊断，无需活检。
