Department of Otolaryngology, Hubei Women and Children Hospital, Wuhan, China.
Am J Otolaryngol. 2010 Mar-Apr;31(2):96-103. doi: 10.1016/j.amjoto.2008.11.008. Epub 2009 Mar 27.
This study was carried out to evaluate the diagnostic value of 226 and 1000 Hz probe-tone tympanometry in infants with effusion in the middle ear.
For this study, we recruited 52 infants with ages 42 days to 6 months as clinical subjects in a hearing-ability screening program. After a spiral computerized tomography (CT) scan of the patients, we tested their hearing using tympanometry of 2 probe-tone frequencies: 226 and 1000 Hz. The patients were divided into 2 groups according to the results of the CT scan: group 1 patients had normal middle ears without fluid, and group 2 patients had ears with fluid. We recorded the tympanograms and their percentage of every type and compared the tympanometric results with CT to get the concordance rate between tympanometry and CT diagnose while obtaining the normal values of 1000 Hz tympanometric measures.
The 226 Hz probe-tone tympanograms of middle ears with fluid differed greatly from those without. At 226 Hz, their tympanograms were single-peaked tympanograms (51.06%), double-peaked tympanograms (44.68%), flat tympanograms (2.13%), and negative-pressure tympanograms (2.13%) for the group with normal middle ears, but single-peaked tympanograms (77.19%), double-peaked tympanograms (19.30%), and flat tympanograms (3.51%) for the group with middle ear effusion. The 1000 Hz probe-tone tympanograms included single-peaked or flat-type tympanograms in both the normal middle ear group and the group with middle ear effusion. The group with normal middle ears was identified by spiral CT, and its tympanograms mostly had a single peak (97.87%) during 1000 Hz tympanometry. Tympanograms of the middle ear effusion group mostly had a flat curve (98.25%). When the Liden/Jerger classification system was used to evaluate the tympanograms, normal tympanograms were single-peaked, and flat tympanograms indicated middle ear effusion. According to this standard, the concordance rate between the 1000 Hz tympanometry (98.08%) and CT diagnosis was higher than when 226 Hz tympanometry (25%) (P < .05) was performed, and the value of kappa was equal to 0.961 between 1000 Hz tympanometry and CT diagnosis.
In clinical practice, 1000 Hz tympanometry, not 226 Hz, is recommended to determine the presence of middle ear fluid in infants younger than 6 months.
本研究旨在评估 226Hz 和 1000Hz 探测音鼓室图在中耳积液婴儿中的诊断价值。
在听力筛查计划中,我们招募了 52 名年龄在 42 天至 6 个月的婴儿作为临床研究对象。对患者进行螺旋 CT 扫描后,我们使用 2 种探测音频率(226Hz 和 1000Hz)对其听力进行测试。根据 CT 扫描结果,患者被分为 2 组:组 1 患者中耳无积液,组 2 患者中耳有积液。我们记录鼓室图及其各类型的百分比,并将鼓室图结果与 CT 结果进行比较,以获得鼓室图与 CT 诊断的一致性率,同时获得 1000Hz 鼓室测量的正常值。
中耳积液组的 226Hz 探测音鼓室图与无积液组有很大差异。在 226Hz 时,组 1 中耳正常的鼓室图为单峰型(51.06%)、双峰型(44.68%)、平坦型(2.13%)和负压型(2.13%),而组 2 中耳积液的鼓室图为单峰型(77.19%)、双峰型(19.30%)和平坦型(3.51%)。在 1000Hz 探测音时,中耳正常组和中耳积液组的鼓室图均为单峰或平坦型。通过螺旋 CT 确定中耳正常组,其鼓室图在 1000Hz 鼓室测量时大多为单峰(97.87%)。中耳积液组的鼓室图大多为平坦曲线(98.25%)。当使用 Liden/Jerger 分类系统评估鼓室图时,正常鼓室图为单峰型,平坦鼓室图则表示中耳积液。根据这一标准,1000Hz 鼓室图(98.08%)与 CT 诊断的一致性率高于 226Hz 鼓室图(25%)(P<.05),并且 1000Hz 鼓室图与 CT 诊断的kappa 值等于 0.961。
在临床实践中,建议使用 1000Hz 鼓室图而非 226Hz 鼓室图来确定 6 个月以下婴儿中耳积液的存在。