Campos Ualace De Paula, Hatzopoulos Stavros, Śliwa Lech K, Skarżyński Piotr H, Jędrzejczak Wiesław W, Skarżyński Henryk, Carvallo Renata Mota Mamede
Department of Physical Therapy, Speech Therapy and Occupational Therapy, University of São Paulo of Medicine, São Paulo, SP, Brazil.
Audiology and ENT Department, University of Ferrara, Ferrara, Italy.
Med Sci Monit. 2016 Jun 14;22:2028-34. doi: 10.12659/msm.897157.
BACKGROUND Pathologies that alter the impedance of the middle ear may consequently modify the DPOAE amplitude. The aim of this study was to correlate information from 2 different clinical procedures assessing middle ear status. Data from DPOAE responses (both DP-Gram and DP I/O functions) were correlated with data from multi-component tympanometry at 1000 Hz. MATERIAL AND METHODS The subjects were divided into a double-peak group (DPG) and a single-peak group (SPG) depending on 1000 Hz tympanogram pattern. Exclusion criteria (described in the Methods section) were applied to both groups and finally only 31 ears were assigned to each group. The subjects were also assessed with traditional tympanometry and behavioral audiometry. RESULTS Compared to the single-peak group, in terms of the 226 Hz tympanometry data, subjects in the DPG group presented: (i) higher values of ear canal volume; (ii) higher peak pressure, and (iii) significantly higher values of acoustic admittance. DPOAE amplitudes were lower in the DPG group only at 6006 Hz, but the difference in amplitude between the DPG and SPG groups decreased as the frequency increased. Statistical differences were observed only at 1001 Hz and a borderline difference at 1501 Hz. In terms of DPOAE I/O functions, significant differences were observed only in 4 of the 50 tested points. CONCLUSIONS The 1000-Hz tympanometric pattern significantly affects the structure of DPOAE responses only at 1001 Hz. In this context, changes in the properties of the middle ear (as detected by the 1000 Hz tympanometry) can be considered as prime candidates for the observed variability in the DP-grams and the DP I/O functions.
改变中耳阻抗的病理状况可能会相应地改变畸变产物耳声发射（DPOAE）的幅度。本研究的目的是关联来自评估中耳状态的两种不同临床程序的信息。DPOAE反应数据（包括DP-gram和DP I/O函数）与1000Hz多成分鼓室图数据相关。材料与方法：根据1000Hz鼓室图模式将受试者分为双峰组（DPG）和单峰组（SPG）。两组均应用排除标准（方法部分有描述），最终每组仅分配31只耳。还对受试者进行了传统鼓室图检查和行为测听。结果：与单峰组相比，在226Hz鼓室图数据方面，DPG组受试者表现为：（i）耳道容积值更高；（ii）峰值压力更高，以及（iii）声导纳值显著更高。DPG组仅在6006Hz时DPOAE幅度较低，但DPG组和SPG组之间的幅度差异随着频率增加而减小。仅在1001Hz观察到统计学差异，在1501Hz观察到临界差异。在DPOAE I/O函数方面，仅在50个测试点中的4个观察到显著差异。结论：1000Hz鼓室图模式仅在1001Hz时显著影响DPOAE反应的结构。在这种情况下，中耳特性的变化（如通过1000Hz鼓室图检测到的）可被视为观察到的DP-gram和DP I/O函数变异性的主要候选因素。
