Zagouri Flora, Papaefthimiou Maria, Chalazonitis Athanasios N, Antoniou Nikolaos, Dimopoulos Meletios-Athanasios, Bamias Aristotle
Department of Clinical Therapeutics, Athens University, School of Medicine, Athens, Greece.
Onkologie. 2009 Dec;32(12):758-61. doi: 10.1159/000255336. Epub 2009 Nov 20.
The most common sites of metastasis in prostate cancer include bone and regional lymph nodes followed by lung, liver, and brain. Peritoneal metastasis without skeletal involvement is extremely rare.
We present herein a patient with hormone refractory prostate cancer with peritoneal metastasis accompanied by ascites but without bone metastasis. The patient initially experienced an excellent response to docetaxel-based chemotherapy.
Prostate cancer can present with distant metastasis in unexpected sites. The lack of skeletal involvement does not exclude the possibility of distant metastases. The presence of ascites may indicate peritoneal disease which could be responsive to current standard chemotherapy.
前列腺癌最常见的转移部位包括骨骼和区域淋巴结，其次是肺、肝和脑。无骨骼受累的腹膜转移极为罕见。
我们在此报告一名激素难治性前列腺癌患者，伴有腹膜转移和腹水，但无骨转移。该患者最初对基于多西他赛的化疗反应良好。
前列腺癌可在意外部位出现远处转移。无骨骼受累并不排除远处转移的可能性。腹水的存在可能提示腹膜疾病，对当前标准化疗可能有反应。
