Ani Ifeanyi, Costaldi Mark, Abouassaly Robert
Department of Urology, University Hospitals Case Medical Center, Cleveland, OH;
Can Urol Assoc J. 2013 Mar-Apr;7(3-4):E248-50. doi: 10.5489/cuaj.547.
Malignant ascites from advanced prostate cancer is rare and has a poor prognosis. We report a case of a 57-year-old African American male presenting with weight loss, lower urinary tract symptoms and voiding dysfunction. He also had renal failure with metabolic abnormalities associated with significant abdominal distention and pain. Computed tomography showed ascites, which was pathologically confirmed by immunostaining and cytological identification of malignant cells. Prostate biopsy identified high-grade prostate cancer which responded to hormonal therapy with a significant decrease in serum prostatic-specific antigen. Ascites was managed with paracentesis and renal failure with hemodialysis as needed.
晚期前列腺癌所致恶性腹水较为罕见，预后较差。我们报告一例57岁非裔美国男性患者，出现体重减轻、下尿路症状及排尿功能障碍。他还伴有肾衰竭及代谢异常，伴有明显腹胀和疼痛。计算机断层扫描显示有腹水，经免疫染色及恶性细胞的细胞学鉴定病理证实。前列腺活检确诊为高级别前列腺癌，该患者对激素治疗有反应，血清前列腺特异性抗原显著下降。腹水通过腹腔穿刺术处理，肾衰竭则根据需要进行血液透析。
